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European Journal of Clinical Microbiology & Infectious Diseases

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Open Access 01-12-2018 | Original Article

Large variation in ESBL-producing Escherichia coli carriers in six European countries including Russia

Authors: Sofia Ny, Roman Kozlov, Uga Dumpis, Petra Edquist, Kirsi Gröndahl-Yli-Hannuksela, Anna-Maria Kling, Danuta O. Lis, Christoph Lübbert, Monika Pomorska-Wesołowska, Ivan Palagin, Aija Vilde, Jaana Vuopio, Jan Walter, Karin Tegmark Wisell, NoDARS ESBL-carrier working group

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 12/2018

Abstract

We investigated the faecal carriage prevalence of extended-spectrum β-lactamase production in Escherichia coli (EP-EC) and/or Klebsiella pneumoniae (EP-KP) and risk factors associated with carriage among adult study subjects in Finland, Germany, Latvia, Poland, Russia and Sweden (partner countries). The aim was to get indicative data on the prevalence of ESBL-carriage in specific populations in the region. Faecal samples were collected from four study populations and screened on ChromID-ESBL and ChromID-OXA-48 plates. Positive isolates were further characterised phenotypically. Our results show a large variation in carrier prevalence ranging from 1.6% in Latvia to 23.2% in Russia for EP-EC. For the other partner countries, the prevalence of EP-EC were in increasing numbers, 2.3% for Germany, 4.7% for Finland, 6.6% for Sweden, 8.0% for Poland and 8.1% for all partner countries in total. Carriers of EP-KP were identified only in Finland, Russia and Sweden, and the prevalence was < 2% in each of these countries. No carriers of carbapenemase-producing isolates were identified. This is the first study reporting prevalence of carriers (excluding traveller studies) for Finland, Latvia, Poland and Russia. It contributes with important information regarding the prevalence of EP-EC and EP-KP carriage in regions where studies on carriers are limited.

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Title: Large variation in ESBL-producing Escherichia coli carriers in six European countries including Russia
Authors: Sofia Ny
Roman Kozlov
Uga Dumpis
Petra Edquist
Kirsi Gröndahl-Yli-Hannuksela
Anna-Maria Kling
Danuta O. Lis
Christoph Lübbert
Monika Pomorska-Wesołowska
Ivan Palagin
Aija Vilde
Jaana Vuopio
Jan Walter
Karin Tegmark Wisell
NoDARS ESBL-carrier working group
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 12/2018
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-018-3382-8

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