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Published in: European Journal of Clinical Microbiology & Infectious Diseases 11/2018

01-11-2018 | Review

Current taxonomy of Rhodococcus species and their role in infections

Authors: Mohadeseh Majidzadeh, Mehdi Fatahi-Bafghi

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 11/2018

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Abstract

Rhodococcus is a genus of obligate aerobic, Gram-positive, partially acid-fast, catalase-positive, non-motile, and none-endospore bacteria. The genus Rhodococcus was first introduced by Zopf. This bacterium can be isolated from various sources of the environment and can grow well in non-selective medium. A large number of phenotypic characterizations are used to compare different species of the genus Rhodococcus, and these tests are not suitable for accurate identification at the genus and species level. Among nucleic acid-based methods, the most powerful target gene for revealing reliable phylogenetic relationships is 16S ribosomal RNA gene (16S rRNA gene) sequence analysis, but this gene is unable to differentiation some of Rhodococcus species. To date, whole genome sequencing analysis has solved taxonomic complexities in this genus. Rhodococcus equi is the major cause of foal pneumonia, and its implication in human health is related to cases in immunocompromised patients. Macrolide family together with rifampicin is one of the most effective antibiotic agents for treatment rhodococcal infections.
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Metadata
Title
Current taxonomy of Rhodococcus species and their role in infections
Authors
Mohadeseh Majidzadeh
Mehdi Fatahi-Bafghi
Publication date
01-11-2018
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Clinical Microbiology & Infectious Diseases / Issue 11/2018
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-018-3364-x

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