Candidemia complicated by endophthalmitis: a prospective analysis

Excerpt

Endogenous fungal endophthalmitis, including chorioretinitis or vitreal involvement, is a known complication of disseminated candidal infection. The incidence rate of candidal eye infection as a complication of candidemia is unclear. Some studies of ocular candidiasis, many of which were performed retrospectively, report rates varying from 2% to 40% [1‐7]. This variability in incidence may relate to the retrospective nature of these reports, a difference in definition of ocular candidiasis, or other differences in methodology. A few prospective studies report similar rates ranging from approximately 2% to 40% [1‐4, 6, 8‐10]. Therefore, to demonstrate the current incidence of ocular candidiasis, we undertook a prospective study of fungal endophthalmitis as a complication of candidemia in hospitalized patients. …