Published in:
01-07-2004 | Brief Report
Vertebral osteomyelitis and epidural abscess in a patient receiving enfuvirtide
Authors:
J. Portilla, V. Boix, E. Merino, S. Reus, J. M. Seguí, I. Lopez-Azkarreta
Published in:
European Journal of Clinical Microbiology & Infectious Diseases
|
Issue 7/2004
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Excerpt
Reported here is a case of vertebral osteomyelitis and epidural abscess that occurred in a patient receiving enfuvirtide, the first antiretroviral agent to be administered by subcutaneous injection. Since the agent is commonly administered to severely immunocompromised patients, the repeated injections can lead to skin colonization and injury that could be followed by bacteremia and its complications. In addition, certain infections, such as pneumonia, have been related to enfuvirtide use, although a clear pathophysiologic mechanism has not been identified. Patients treated with enfuvirtide need special attention to ensure that a prompt and accurate diagnosis can be made in case complications occur. …