Published in:
01-04-2004 | Concise Article
Persistent Colonization of Nine Cystic Fibrosis Patients with an Achromobacter (Alcaligenes) xylosoxidans Clone
Authors:
M. Kanellopoulou, S. Pournaras, H. Iglezos, N. Skarmoutsou, E. Papafrangas, A. N. Maniatis
Published in:
European Journal of Clinical Microbiology & Infectious Diseases
|
Issue 4/2004
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Abstract
The present study was conducted to investigate the increasing incidence of Achromobacter (previously Alcaligenes) xylosoxidans isolates being recovered from sputum samples of cystic fibrosis patients at a cystic fibrosis department for adults in Athens, Greece. During the 1-year study period, a total of 34 isolates were detected persistently in 9 of 71 cystic fibrosis patients. The isolates exhibited resistance to multiple antimicrobial agents. Isolates that were recovered repeatedly from each patient exhibited identical macrorestriction profiles with pulsed-field gel electrophoresis, indicating that the same strain persisted in the lungs of these patients. Isolates from five of the patients were genetically related, suggesting a common-source outbreak of Achromobacter xylosoxidans colonization or infection.