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Neurological Sciences
Published in: Neurological Sciences 7/2022

05-04-2022 | Multiple Sclerosis | COVID-19

COVID-19 vaccines and patients with multiple sclerosis: willingness, unwillingness and hesitancy: a systematic review and meta-analysis

Authors: Amid Yazdani, Omid Mirmosayyeb, Elham Moases Ghaffary, Mozhgan Sadat Hashemi, Mahsa Ghajarzadeh

Published in: Neurological Sciences | Issue 7/2022

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Abstract

Objective

The purpose of this study was to determine the pooled prevalence of vaccination willingness, unwillingness, and hesitancy among patients with multiple sclerosis.

Methods

Databases including PubMed, Scopus, EMBASE, Web of Science, and Google Scholar were searched. by two expert researchers, as well as references in the included studies, which were published before October 2021.

Results

Three hundred eighty articles were found in four data bases. One hundred eighty-two studies remained following deleting duplicates. Finally, ten studies remained for the meta-analysis. Totally, 5983 patients with MS were assessed. The pooled prevalence of willingness to vaccination among patients with MS was 76% (95% CI: 67–85%) (I2 = 98.4%, p < 0.001). Unwillingness pooled prevalence to vaccination among patients with MS was 2% (95% CI: 2–3%) (I2 = 97.9%, p < 0.001). Hesitancy pooled prevalence to vaccination among patients with MS was 0% (I2 = 98%, p < 0.001).

Conclusion

According to the findings of this systematic review and meta-analysis, more than two-thirds of patients with MS were willing to obtain COVID-19 vaccines.
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Metadata
Title
COVID-19 vaccines and patients with multiple sclerosis: willingness, unwillingness and hesitancy: a systematic review and meta-analysis
Authors
Amid Yazdani
Omid Mirmosayyeb
Elham Moases Ghaffary
Mozhgan Sadat Hashemi
Mahsa Ghajarzadeh
Publication date
05-04-2022
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 7/2022
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-022-06051-6

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