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01-07-2021 | Severe Acute Respiratory Syndrome Coronavirus | COVID-19

Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report

Authors: Marco Bozzali, Alberto Grassini, Giovanni Morana, Michela Zotta, Sara Cabras, Alberto Romagnolo, Carlo Alberto Artusi, Elisa Montalenti, Mario Giorgio Rizzone, Diego Garbossa, Elisa Montanaro, Mara Cercignani, Leonardo Lopiano

Published in: Neurological Sciences | Issue 7/2021

Abstract

We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.

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Title: Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report
Authors: Marco Bozzali
Alberto Grassini
Giovanni Morana
Michela Zotta
Sara Cabras
Alberto Romagnolo
Carlo Alberto Artusi
Elisa Montalenti
Mario Giorgio Rizzone
Diego Garbossa
Elisa Montanaro
Mara Cercignani
Leonardo Lopiano
Publication date: 01-07-2021
Publisher: Springer International Publishing
Keywords: Severe Acute Respiratory Syndrome Coronavirus
SARS-CoV-2
COVID-19
Epilepsy
Encephalitis
Focal Seizure
Published in: Neurological Sciences / Issue 7/2021
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-021-05233-y

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Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report

Abstract

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Abstract

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