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01-10-2020 | Coronavirus | COVID-19

Impact of COVID-19 on neurological manifestations: an overview of stroke presentation in pandemic

Authors: Nida Fatima, Maher Saqqur, Fatima Qamar, Samia Shaukat, Ashfaq Shuaib

Published in: Neurological Sciences | Issue 10/2020

Abstract

Corona virus disease 2019 (COVID-19) pandemic has become a globally challenging issue after its emergence in December 2019 from Wuhan, China. Despite its common presentation as respiratory distress, patients with COVID-19 have also shown neurological manifestation especially stroke. Therefore, the authors sought to determine the etiology, underlying risk factors, and outcomes among patients with COVID-19 presenting with stroke. We conducted a systematic review of the electronic database (PubMed, Google Scholar, Scopus, Medline, EMBASE, and Cochrane library) using different MeSH terms from November 2019 to June 2020. A total of 39 patients with stroke from 6 studies were included. The mean age of our included patients was 61.4 ± 14.2 years. Majority of the patients (n = 36, 92.3%) with COVID-19 had ischemic stroke, 5.1% (n = 2) had hemorrhagic stroke, and 2.6% (n = 1) had cerebral venous thrombosis at the time of initial clinical presentation. Almost all of the patients presented had underlying risk factors predisposing to stroke which included diabetes mellitus, hyperlipidemia, hypertension, and previous history of cerebrovascular disease. 51.2% (n = 20) of the included patients infected with COVID-19 with stroke died, while remaining patients were either discharged home or transferred to a rehabilitation unit. Exploring the neurological manifestation in terms of stroke among patients with COVID-19 is a step towards better understanding of the virus, preventing further spread, and treating the patients affected by this pandemic.

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Title: Impact of COVID-19 on neurological manifestations: an overview of stroke presentation in pandemic
Authors: Nida Fatima
Maher Saqqur
Fatima Qamar
Samia Shaukat
Ashfaq Shuaib
Publication date: 01-10-2020
Publisher: Springer International Publishing
Keywords: Coronavirus
Stroke
COVID-19
Hypertension
Diabetes
Hypertension
Cerebral Hemorrhage
Published in: Neurological Sciences / Issue 10/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04637-6

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