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01-12-2020 | Nerve Stimulation | Review Article

Different modalities of invasive neurostimulation for epilepsy

Authors: Soha A. Alomar, Rothaina J. Saeedi

Published in: Neurological Sciences | Issue 12/2020

Abstract

Epilepsy affects 1% of the general population, about one-third of which is pharmacologically resistant. Uncontrolled seizures are associated with an increased risk of traumatic injury and sudden unexpected death of epilepsy. There is a considerable psychological and financial burden on caregivers of patients with epilepsy, particularly among pediatric patients. Epilepsy surgery, when indicated, is the most promising cure for epilepsy. However, when surgery is contraindicated or refused by the patient, neurostimulation is an alternative palliative approach, albeit with a lower chance of entirely curing patients of seizures. There are many options for neurostimulation. The three most commonly used invasive neurostimulation procedures that consistently show evidence of being safe and efficacious are vagal nerve stimulation, responsive neuro stimulation, or anterior thalamic nucleus deep brain stimulation. The goal of this review is to summarize the current evidence supporting the use of these three techniques, which are approved by most regulatory bodies, and discuss different factors that may enable epilepsy surgeons to choose the most appropriate modality for each patient.

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Title: Different modalities of invasive neurostimulation for epilepsy
Authors: Soha A. Alomar
Rothaina J. Saeedi
Publication date: 01-12-2020
Publisher: Springer International Publishing
Keywords: Nerve Stimulation
Epilepsy
Published in: Neurological Sciences / Issue 12/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04614-z

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Different modalities of invasive neurostimulation for epilepsy

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