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01-09-2020 | Stroke | COVID-19

A single-centre experience of intravenous thrombolysis for stroke in COVID-19 patients

Authors: Davide Sangalli, Valeria Polonia, Daniele Colombo, Vittorio Mantero, Marco Filizzolo, Chiara Scaccabarozzi, Andrea Salmaggi

Published in: Neurological Sciences | Issue 9/2020

Abstract

The sudden worldwide outbreak of Coronavirus Disease 2019 (COVID-19) has certainly provided new challenges in the management of acute ischaemic stroke, and the risk-benefit ratio of intravenous thrombolysis in COVID-19 positive patients is not well known. We describe four COVID-19 patients treated with intravenous thrombolysis for acute ischaemic stroke. Although rt-PA administration is the main therapeutic strategy, our patients experienced unpredictable complications and showed atypical features: the overall mortality was very high. In conclusion, in this article, we provide information about these cases and discuss the possible explanation behind this trend.

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Title: A single-centre experience of intravenous thrombolysis for stroke in COVID-19 patients
Authors: Davide Sangalli
Valeria Polonia
Daniele Colombo
Vittorio Mantero
Marco Filizzolo
Chiara Scaccabarozzi
Andrea Salmaggi
Publication date: 01-09-2020
Publisher: Springer International Publishing
Keywords: Stroke
Endocarditis
COVID-19
Hydroxychloroquine
Aphasia
Published in: Neurological Sciences / Issue 9/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04591-3

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A single-centre experience of intravenous thrombolysis for stroke in COVID-19 patients

Abstract

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