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01-03-2020 | Migraine | Review Article

Personality profile and depression in migraine: a meta-analysis

Authors: Federica Garramone, Chiara Baiano, Antonio Russo, Alfonsina D’Iorio, Gioacchino Tedeschi, Luigi Trojano, Gabriella Santangelo

Published in: Neurological Sciences | Issue 3/2020

Abstract

Background

Despite the clinical importance of psychological factors in migraine, the relationship between personality traits, depression, and migraine has been poorly investigated.

Objective

To delineate the personality profile distinctive for migraineurs and to explore the relationship between personality traits and depression in migraineurs compared to non-migraineurs.

Methods

A systematic literature search was performed up to March 2019 using PsycInfo (PROQUEST), PubMed and Scopus. Sixteen primary studies met inclusion and exclusion criteria and were included in the meta-analysis.

Results

The meta-analysis on the personality defined according to Psychobiological model revealed high Harm Avoidance (Hedges’g = 0.31; 95% confidence interval [CI] = 0.01–0.60), Persistence (Hedges’g = 0.37; 95% CI = 0.01to − 0.72) and low self-directedness (Hedges’g = − 0.33; 95% CI = −0.57 to − 0.09) in migraineurs. The meta-analysis on the personality defined according to Three Factor Model revealed high neuroticism (Hedges’g = 0.47; 95% CI = 0.32–0.63) and low extraversion (Hedges’g = − 0.08; 95% CI = − 0.14 to − 0.03) in migraineurs. Meta-regression analysis revealed that neuroticism moderated the relationship between depression and migraine.

Conclusion

The findings evidenced that migraine is characterized by specific personality traits. Among them, neuroticism influenced the severity of depression in migraineurs, and, therefore, an early evaluation of the personality traits could allow identifying patients susceptible to develop migraine-associated psychopathological symptoms.

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Title: Personality profile and depression in migraine: a meta-analysis
Authors: Federica Garramone
Chiara Baiano
Antonio Russo
Alfonsina D’Iorio
Gioacchino Tedeschi
Luigi Trojano
Gabriella Santangelo
Publication date: 01-03-2020
Publisher: Springer International Publishing
Keywords: Migraine
Affective Disorder
Affective Disorder
Aura
Published in: Neurological Sciences / Issue 3/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-019-04174-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Personality profile and depression in migraine: a meta-analysis

Abstract

Background

Objective

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Objective

Methods

Results

Conclusion

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