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01-10-2019 | Capsaicin | Review Article

Dietary pattern in relation to the risk of Alzheimer’s disease: a systematic review

Authors: Mehnoosh Samadi, Shima Moradi, Mehdi Moradinazar, Roghayeh Mostafai, Yahya Pasdar

Published in: Neurological Sciences | Issue 10/2019

Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative disease leading to a gradual and irreversible loss of memory, linguistic skills, and perception of time and space, thinking, and behavior. Dietary pattern has been presented as a contributor to the incidence of Alzheimer’s. This study aimed at reviewing the evidence on the relation between dietary pattern and AD. This systematic search was performed on the articles available in PubMed, Scopus, and Web of Sciences databases until May 2019 using keywords, including (diet, food, dietary pattern, food pattern) and (Alzheimer’s disease) among observational studies. After excluding duplicated, and irrelevant studies, 26 studies were eligible for this review study. We categorized the studied dietary patterns into two groups: healthy and unhealthy diet. This study reviewed two case-control, five cross-sectional, and 19 prospective studies. Eight studies assessed unhealthy diet (high-fat diet, high-glycemic diet, sweetened sugary beverage, etc.) and the risk of AD. In addition, the other studies considered the effect of healthy diet such as Mediterranean diet, dietary approaches to stop hypertension (DASH), Mediterranean-DASH intervention for neurodegenerative delay, and seafood-rich diet on AD. This literature review indicated that adherence to a healthy dietary pattern has neuroprotective effects on AD prevention, while unhealthy diet can cause neurodegenerative effects in AD etiology. In conclusion, our findings showed that adherence to healthy diet can decrease oxidative stress and inflammation and accumulation of amyloid-β and consequently can decrease the risk of AD.

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Blennow K, de Leon MJ, Zetterberg H (2006) Alzheimer’s disease. Lancet (London, England) 368(9533):387–403. https://doi.org/10.1016/s0140-6736(06)69113-7 CrossRef

Association As (2017) 2017 Alzheimer’s disease facts and figures. Alzheimers Dement 13(4):325–373CrossRef

Hebert LE, Weuve J, Scherr PA, Evans DA (2013) Alzheimer disease in the United States (2010–2050) estimated using the 2010 census. Neurology 80(19):1778–1783PubMedPubMedCentralCrossRef

Hebert L, Bienias J, Aggarwal N, Wilson R, Bennett D, Shah R, Evans D (2010) Change in risk of Alzheimer disease over time. Neurology 75(9):786–791PubMedPubMedCentralCrossRef

Green RC, Cupples LA, Go R, Benke KS, Edeki T, Griffith PA, Williams M, Hipps Y, Graff-Radford N, Bachman D (2002) Risk of dementia among white and African American relatives of patients with Alzheimer disease. Jama 287(3):329–336PubMedCrossRef

Tyas SL, Manfreda J, Strain LA, Montgomery PR (2001) Risk factors for Alzheimer’s disease: a population-based, longitudinal study in Manitoba, Canada. Int J Epidemiol 30(3):590–597PubMedCrossRef

Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PS, Pericak-Vance M, Joo S, Rosi B, Gusella J, Crapper-MacLachlan D, Alberts M (1993) Association of apolipoprotein E allele ϵ4 with late-onset familial and sporadic Alzheimer’s disease. Neurology 43(8):1467–1467PubMedCrossRef

Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, Van Duijn CM (1997) Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis. Jama 278(16):1349–1356PubMedCrossRef

Baumgart M, Snyder HM, Carrillo MC, Fazio S, Kim H, Johns H (2015) Summary of the evidence on modifiable risk factors for cognitive decline and dementia: a population-based perspective. Alzheimers Dement 11(6):718–726PubMedCrossRef

10.

Hill E, Clifton P, Goodwill AM, Dennerstein L, Campbell S, Szoeke C (2018) Dietary patterns and β-amyloid deposition in aging Australian women. Alzheimer’s & Dementia: Translational Research & Clinical Interventions

11.

Taylor MK, Sullivan DK, Swerdlow RH, Vidoni ED, Morris JK, Mahnken JD, Burns JM (2017) A high-glycemic diet is associated with cerebral amyloid burden in cognitively normal older adults. Am J Clin Nutr 106(6):1463–1470PubMedPubMedCentralCrossRef

12.

Gu Y, Schupf N, Cosentino S, Luchsinger J, Scarmeas N (2012) Nutrient intake and plasma β-amyloid. Neurology 78(23):1832–1840PubMedPubMedCentralCrossRef

13.

Wang J, Ho L, Qin W, Rocher AB, Seror I, Humala N, Maniar K, Dolios G, Wang R, Hof PR (2005) Caloric restriction attenuates β-amyloid neuropathology in a mouse model of Alzheimer’s disease. FASEB J 19(6):659–661PubMedCrossRef

14.

Merrill DA, Siddarth P, Raji CA, Emerson ND, Rueda F, Ercoli LM, Miller KJ, Lavretsky H, Harris LM, Burggren AC (2016) Modifiable risk factors and brain positron emission tomography measures of amyloid and tau in nondemented adults with memory complaints. Am J Geriatr Psychiatry 24(9):729–737PubMedPubMedCentralCrossRef

15.

Luchsinger J, Tang M, Mayeux R (2007) Glycemic load and risk of Alzheimer’s disease. The Journal of Nutrition, Health & Aging 11(3):238

16.

Ylilauri MP, Voutilainen S, Lönnroos E, Mursu J, Virtanen HE, Koskinen TT, Salonen JT, Tuomainen T-P, Virtanen JK (2017) Association of dietary cholesterol and egg intakes with the risk of incident dementia or Alzheimer disease: the Kuopio Ischaemic Heart Disease Risk Factor Study, 2. Am J Clin Nutr 105(2):476–484PubMedCrossRef

17.

Dernini S, Berry EM (2015) Mediterranean diet: from a healthy diet to a sustainable dietary pattern. Frontiers in nutrition 2:15PubMedPubMedCentralCrossRef

18.

Francis HM, Stevenson RJ (2011) Higher reported saturated fat and refined sugar intake is associated with reduced hippocampal-dependent memory and sensitivity to interoceptive signals. Behav Neurosci 125(6):943–955PubMedCrossRef

19.

Gu Y, Luchsinger JA, Stern Y, Scarmeas N (2010) Mediterranean diet, inflammatory and metabolic biomarkers, and risk of Alzheimer’s disease. J Alzheimers Dis 22(2):483–492PubMedPubMedCentralCrossRef

20.

Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA (2015) Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Systematic Reviews 4(1). https://doi.org/10.1186/2046-4053-4-1

21.

Scale N-O, Wells G, Shea B, O’Connell D, Peterson J, Welch V, Losos M, al e (2014) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses

22.

Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Schneider J, Wilson RS (2003) Dietary fats and the risk of incident Alzheimer disease. Arch Neurol 60(2):194–200PubMedCrossRef

23.

Laitinen M, Ngandu T, Rovio S, Helkala E-L, Uusitalo U, Viitanen M, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M (2006) Fat intake at midlife and risk of dementia and Alzheimer’s disease: a population-based study. Dement Geriatr Cogn Disord 22(1):99–107PubMedCrossRef

24.

Hill E, Clifton P, Goodwill AM, Dennerstein L, Campbell S, Szoeke C (2018) Dietary patterns and β-amyloid deposition in aging Australian women. Alzheimer’s and Dementia: Translational Research and Clinical Interventions 4:535–541. https://doi.org/10.1016/j.trci.2018.09.007 CrossRefPubMedPubMedCentral

25.

Pase MP, Himali JJ, Jacques PF, DeCarli C, Satizabal CL, Aparicio H, Vasan RS, Beiser AS, Seshadri S (2017) Sugary beverage intake and preclinical Alzheimer’s disease in the community. Alzheimers Dement 13(9):955–964PubMedCrossRefPubMedCentral

26.

Gu Y, Nieves JW, Luchsinger JA, Scarmeas N (2011) Dietary inflammation factor rating system and risk of Alzheimer disease in elders. Alzheimer Dis Assoc Disord 25(2):149–154. https://doi.org/10.1097/WAD.0b013e3181ff3c6a CrossRefPubMedPubMedCentral

27.

Gustaw-Rothenberg K (2009) Dietary patterns associated with Alzheimer’s disease: population based study. Int J Environ Res Public Health 6(4):1335–1340. https://doi.org/10.3390/ijerph6041335 CrossRefPubMedPubMedCentral

28.

Scarmeas N, Stern Y, Tang MX, Mayeux R, Luchsinger JA (2006) Mediterranean diet and risk for Alzheimer’s disease. Ann Neurol 59(6):912–921PubMedPubMedCentralCrossRef

29.

Scarmeas N, Stern Y, Mayeux R, Luchsinger JA (2006) Mediterranean diet, Alzheimer disease, and vascular mediation. Arch Neurol 63(12):1709–1717. https://doi.org/10.1001/archneur.63.12.noc60109 CrossRefPubMedPubMedCentral

30.

Scarmeas N, Luchsinger JA, Schupf N, Brickman AM, Cosentino S, Tang MX, Stern Y (2009) Physical activity, diet, and risk of Alzheimer disease. Jama 302(6):627–637PubMedPubMedCentralCrossRef

31.

Gu Y, Luchsinger JA, Stern Y, Scarmeas N (2010) Mediterranean diet, inflammatory and metabolic biomarkers, and risk of Alzheimer’s disease. J Alzheimer Dis 22(2):483–492. https://doi.org/10.3233/jad-2010-100897 CrossRef

32.

Gardener S, Gu Y, Rainey-Smith SR, Keogh JB, Clifton PM, Mathieson S, Taddei K, Mondal A, Ward VK, Scarmeas N (2012) Adherence to a Mediterranean diet and Alzheimer’s disease risk in an Australian population. Transl Psychiatry 2(10):e164PubMedPubMedCentralCrossRef

33.

Mosconi L, Murray J, Tsui W, Li Y, Davies M, Williams S, Pirraglia E, Spector N, Osorio R, Glodzik L (2014) Mediterranean diet and magnetic resonance imaging-assessed brain atrophy in cognitively normal individuals at risk for Alzheimer’s disease. J Prev Alzheimers Dis 1(1):23PubMedPubMedCentral

34.

Morris MC, Tangney CC, Wang Y, Sacks FM, Bennett DA, Aggarwal NT (2015) MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimers Dement 11(9):1007–1014PubMedPubMedCentralCrossRef

35.

Olsson E, Karlstrom B, Kilander L, Byberg L, Cederholm T, Sjogren P (2015) Dietary patterns and cognitive dysfunction in a 12-year follow-up study of 70 year old men. J Alzheimer Dis 43(1):109–119. https://doi.org/10.3233/jad-140867 CrossRef

36.

Vassilaki M, Aakre JA, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Alhurani RE, Staubo SC, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO (2018) Mediterranean diet, its components, and amyloid imaging biomarkers. J Alzheimers Dis 64(1):281–290. https://doi.org/10.3233/JAD-171121 CrossRefPubMedPubMedCentral

37.

Calil SRB, Brucki SMD, Nitrini R, Yassuda MS (2018) Adherence to the Mediterranean and MIND diets is associated with better cognition in healthy seniors but not in MCI or AD. Clinical Nutrition ESPEN 28:201–207. https://doi.org/10.1016/j.clnesp.2018.08.001 CrossRefPubMed

38.

Fernando W, Rainey-Smith SR, Gardener SL, Villemagne VL, Burnham SC, Macaulay SL, Brown BM, Gupta VB, Sohrabi HR, Weinborn M, Taddei K, Laws SM, Goozee K, Ames D, Fowler C, Maruff P, Masters CL, Salvado O, Rowe CC, Martins RN (2018) Associations of dietary protein and fiber intake with brain and blood amyloid-beta. J Alzheimer Dis 61(4):1589–1598. https://doi.org/10.3233/jad-170742 CrossRef

39.

Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS, Aggarwal N, Schneider J (2003) Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol 60(7):940–946PubMedCrossRef

40.

Morris MC, Brockman J, Schneider JA, Wang Y, Bennett DA, Tangney CC, van de Rest O (2016) Association of seafood consumption, brain mercury level, and APOE ε4 status with brain neuropathology in older adults. Jama 315(5):489–497PubMedPubMedCentralCrossRef

41.

Devore EE, Grodstein F, van Rooij FJ, Hofman A, Rosner B, Stampfer MJ, Witteman JC, Breteler MM (2009) Dietary intake of fish and omega-3 fatty acids in relation to long-term dementia risk. Am J Clin Nutr 90(1):170–176. https://doi.org/10.3945/ajcn.2008.27037 CrossRefPubMedPubMedCentral

42.

Ozawa M, Ninomiya T, Ohara T, Doi Y, Uchida K, Shirota T, Yonemoto K, Kitazono T, Kiyohara Y (2013) Dietary patterns and risk of dementia in an elderly Japanese population: the Hisayama Study. Am J Clin Nutr 97(5):1076–1082. https://doi.org/10.3945/ajcn.112.045575 CrossRefPubMed

43.

Liu C-H, Bu X-L, Wang J, Zhang T, Xiang Y, Shen L-L, Wang Q-H, Deng B, Wang X, Zhu C (2016) The associations between a capsaicin-rich diet and blood amyloid-β levels and cognitive function. J Alzheimers Dis 52(3):1081–1088PubMedCrossRef

44.

Mosconi L, Murray J, Davies M, Williams S, Pirraglia E, Spector N, Tsui WH, Li Y, Butler T, Osorio RS, Glodzik L, Vallabhajosula S, McHugh P, Marmar CR, de Leon MJ (2014) Nutrient intake and brain biomarkers of Alzheimer’s disease in at-risk cognitively normal individuals: a cross-sectional neuroimaging pilot study. BMJ Open 4(6):e004850. https://doi.org/10.1136/bmjopen-2014-004850 CrossRefPubMedPubMedCentral

45.

Liu CH, Bu XL, Wang J, Zhang T, Xiang Y, Shen LL, Wang QH, Deng B, Wang X, Zhu C, Yao XQ, Zhang M, Zhou HD, Wang YJ (2016) The associations between a capsaicin-rich diet and blood amyloid-β levels and cognitive function. J Alzheimers Dis 52(3):1081–1088. https://doi.org/10.3233/JAD-151079 CrossRefPubMed

46.

Morris MC, Brockman J, Schneider JA, Wang Y, Bennett DA, Tangney CC, van de Rest O (2016) Association of seafood consumption, brain mercury level, and APOE epsilon4 status with brain neuropathology in older adults. Jama 315(5):489–497. https://doi.org/10.1001/jama.2015.19451 CrossRefPubMedPubMedCentral

47.

Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Schneider J, Wilson RS (2003) Dietary fats and the risk of incident Alzheimer disease. Arch Neurol 60(2):194–200PubMedCrossRef

48.

49.

Laitinen MH, Ngandu T, Rovio S, Helkala EL, Uusitalo U, Viitanen M, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M (2006) Fat intake at midlife and risk of dementia and Alzheimer’s disease: a population-based study. Dement Geriatr Cogn Disord 22(1):99–107. https://doi.org/10.1159/000093478 CrossRefPubMed

50.

Scarmeas N, Stern Y, Tang MX, Mayeux R, Luchsinger JA (2006) Mediterranean diet and risk for Alzheimer’s disease. Ann Neurol 59(6):912–921. https://doi.org/10.1002/ana.20854 CrossRefPubMedPubMedCentral

51.

Luchsinger JA, Tang MX, Mayeux R (2007) Glycemic load and risk of Alzheimer’s disease. J Nutr Health Aging 11(3):238–241PubMed

52.

Scarmeas N, Stern Y, Mayeux R, Manly JJ, Schupf N, Luchsinger JA (2009) Mediterranean diet and mild cognitive impairment. Arch Neurol 66(2):216–225. https://doi.org/10.1001/archneurol.2008.536 CrossRefPubMedPubMedCentral

53.

Gu YA, Nieves JW, Stern Y, Luchsinger JA, Scarmeas N (2010) Food combination and Alzheimer disease risk a protective diet. Arch Neurol 67(6):699–706. https://doi.org/10.1001/archneurol.2010.84 CrossRefPubMedPubMedCentral

54.

Eskelinen MH, Ngandu T, Tuomilehto J, Soininen H, Kivipelto M (2011) Midlife healthy-diet index and late-life dementia and Alzheimer’s disease. Dement Geriatr Cogn Dis Extra 1(1):103–112PubMedPubMedCentralCrossRef

55.

Gardener S, Gu Y, Rainey-Smith SR, Keogh JB, Clifton PM, Mathieson SL, Taddei K, Mondal A, Ward VK, Scarmeas N, Barnes M, Ellis KA, Head R, Masters CL, Ames D, Macaulay SL, Rowe CC, Szoeke C, Martins RN (2012) Adherence to a Mediterranean diet and Alzheimer’s disease risk in an Australian population. Transl Psychiatry 2:e164. https://doi.org/10.1038/tp.2012.91 CrossRefPubMedPubMedCentral

56.

Berti V, Murray J, Davies M, Spector N, Tsui WH, Li Y, Williams S, Pirraglia E, Vallabhajosula S, McHugh P, Pupi A, de Leon MJ, Mosconi L (2015) Nutrient patterns and brain biomarkers of Alzheimer’s disease in cognitively normal individuals. J Nutr Health Aging 19(4):413–423. https://doi.org/10.1007/s12603-014-0534-0 CrossRefPubMedPubMedCentral

57.

Morris MC, Tangney CC, Wang YM, Sacks FM, Bennett DA, Aggarwal NT (2015) MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimers Dement 11(9):1007–1014. https://doi.org/10.1016/j.jalz.2014.11.009 CrossRefPubMedPubMedCentral

58.

Pase MP, Himali JJ, Jacques PF, DeCarli C, Satizabal CL, Aparicio H, Vasan RS, Beiser AS, Seshadri S (2017) Sugary beverage intake and preclinical Alzheimer’s disease in the community. Alzheimer Dementia 13(9):955–964. https://doi.org/10.1016/j.jalz.2017.01.024 CrossRef

59.

Ylilauri MPT, Voutilainen S, Lönnroos E, Mursu J, Virtanen HEK, Koskinen TT, Salonen JT, Tuomainen TP, Virtanen JK (2017) Association of dietary cholesterol and egg intakes with the risk of incident dementia or Alzheimer disease: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Clin Nutr 105(2):476–484. https://doi.org/10.3945/ajcn.116.146753 CrossRefPubMed

60.

de Ridder D, Kroese F, Evers C, Adriaanse M, Gillebaart M (2017) Healthy diet: health impact, prevalence, correlates, and interventions. Psychol Health 32(8):907–941PubMedCrossRef

61.

Lv N, Xiao L, Ma J (2014) Dietary pattern and asthma: a systematic review and meta-analysis. J Asthma Allergy 7:105PubMedPubMedCentral

62.

Schwingshackl L, Hoffmann G (2015) Adherence to Mediterranean diet and risk of cancer: an updated systematic review and meta-analysis of observational studies. Cancer Med 4(12):1933–1947PubMedPubMedCentralCrossRef

63.

Sleiman D, Al-Badri MR, Azar ST (2015) Effect of Mediterranean diet in diabetes control and cardiovascular risk modification: a systematic review. Front Public Health 3:69PubMedPubMedCentralCrossRef

64.

Widmer RJ, Flammer AJ, Lerman LO, Lerman A (2015) The Mediterranean diet, its components, and cardiovascular disease. Am J Med 128(3):229–238PubMedCrossRef

65.

Hardman RJ, Kennedy G, Macpherson H, Scholey AB, Pipingas A (2016) Adherence to a Mediterranean-style diet and effects on cognition in adults: a qualitative evaluation and systematic review of longitudinal and prospective trials. Front Nutr 3:22PubMedPubMedCentralCrossRef

66.

Koloverou E, Panagiotakos D, Pitsavos C, Chrysohoou C, Georgousopoulou E, Grekas A, Christou A, Chatzigeorgiou M, Skoumas I, Tousoulis D (2016) Adherence to Mediterranean diet and 10-year incidence (2002–2012) of diabetes: correlations with inflammatory and oxidative stress biomarkers in the ATTICA cohort study. Diabetes Metab Res Rev 32(1):73–81PubMedCrossRef

67.

Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, Roberts RO (2014) Association of mediterranean diet with mild cognitive impairment and Alzheimer’s disease: a systematic review and meta-analysis. J Alzheimers Dis 39(2):271–282PubMedPubMedCentralCrossRef

68.

Rai SK, Fung TT, Lu N, Keller SF, Curhan GC, Choi HK (2017) The Dietary Approaches to Stop Hypertension (DASH) diet, Western diet, and risk of gout in men: prospective cohort study. bmj 357:j1794PubMedPubMedCentralCrossRef

69.

Siervo M, Lara J, Chowdhury S, Ashor A, Oggioni C, Mathers JC (2015) Effects of the Dietary Approach to Stop Hypertension (DASH) diet on cardiovascular risk factors: a systematic review and meta-analysis. Br J Nutr 113(1):1–15PubMedCrossRef

70.

Tangney CC, Li H, Wang Y, Barnes L, Schneider JA, Bennett DA, Morris MC (2014) Relation of DASH-and Mediterranean-like dietary patterns to cognitive decline in older persons. Neurology 83(16):1410–1416PubMedPubMedCentralCrossRef

71.

Siti HN, Kamisah Y, Kamsiah J (2015) The role of oxidative stress, antioxidants and vascular inflammation in cardiovascular disease (a review). Vasc Pharmacol 71:40–56CrossRef

72.

Fiocco AJ, Shatenstein B, Ferland G, Payette H, Belleville S, Kergoat M-J, Morais JA, Greenwood CE (2012) Sodium intake and physical activity impact cognitive maintenance in older adults: the NuAge Study. Neurobiol Aging 33(4):829. e821–829. e828CrossRef

73.

Nowak KL, Fried L, Jovanovich A, Ix J, Yaffe K, You Z, Chonchol M (2018) Dietary sodium/potassium intake does not affect cognitive function or brain imaging indices. Am J Nephrol 47(1):57–65PubMedCrossRef

74.

Marcason W (2015) What are the components to the MIND diet? J Acad Nutr Diet 115(10):1744PubMedCrossRef

75.

Berendsen AM, Kang J, Feskens E, de Groot C, Grodstein F, Van de Rest O (2018) Association of long-term adherence to the mind diet with cognitive function and cognitive decline in American women. J Nutr Health Aging 22(2):222–229PubMedCrossRef

76.

Samieri C, Morris M-C, Bennett DA, Berr C, Amouyel P, Dartigues J-F, Tzourio C, Chasman DI, Grodstein F (2017) Fish intake, genetic predisposition to Alzheimer disease, and decline in global cognition and memory in 5 cohorts of older persons. Am J Epidemiol 187(5):933–940PubMedCentralCrossRef

77.

Connor WE, Connor SL (2007) The importance of fish and docosahexaenoic acid in Alzheimer disease. Oxford University Press,

78.

Avraham Y, Grigoriadis N, Magen I, Poutahidis T, Vorobiav L, Zolotarev O, Ilan Y, Mechoulam R, Berry E (2009) Capsaicin affects brain function in a model of hepatic encephalopathy associated with fulminant hepatic failure in mice. Br J Pharmacol 158(3):896–906PubMedPubMedCentralCrossRef

79.

Kang C, Wang B, Kaliannan K, Wang X, Lang H, Hui S, Huang L, Zhang Y, Zhou M, Chen M (2017) Gut microbiota mediates the protective effects of dietary capsaicin against chronic low-grade inflammation and associated obesity induced by high-fat diet. MBio 8(3):e00470–e00417PubMedPubMedCentral

80.

Hariharan D, Vellanki K, Kramer H (2015) The Western diet and chronic kidney disease. Curr Hypertens Rep 17(3):16. https://doi.org/10.1007/s11906-014-0529-6 CrossRefPubMed

81.

Manzel A, Muller DN, Hafler DA, Erdman SE, Linker RA, Kleinewietfeld M (2014) Role of “Western diet” in inflammatory autoimmune diseases. Curr Allergy Asthma Rep 14(1):404PubMedPubMedCentralCrossRef

82.

Hsu TM, Kanoski SE (2014) Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia. Front Aging Neurosci 6:88PubMedPubMedCentralCrossRef

83.

Kleemann R, Verschuren L, van Erk MJ, Nikolsky Y, Cnubben NH, Verheij ER, Smilde AK, Hendriks HF, Zadelaar S, Smith GJ (2007) Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis. Genome Biol 8(9):R200PubMedPubMedCentralCrossRef

84.

Cao D, Lu H, Lewis TL, Li L (2007) Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease. J Biol Chem 282(50):36275–36282PubMedCrossRef

Title: Dietary pattern in relation to the risk of Alzheimer’s disease: a systematic review
Authors: Mehnoosh Samadi
Shima Moradi
Mehdi Moradinazar
Roghayeh Mostafai
Yahya Pasdar
Publication date: 01-10-2019
Publisher: Springer International Publishing
Keywords: Capsaicin
Alzheimer's Disease
Alzheimer's Disease
Published in: Neurological Sciences / Issue 10/2019
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-019-03976-3

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Dietary pattern in relation to the risk of Alzheimer’s disease: a systematic review

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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