Published in:
01-05-2019 | Migraine | Focus on
Catastrophizing attitude changes after onabotulinumtoxin A treatment in chronic migraine
Authors:
Licia Grazzi, Eleonora Grignani, Emanuela Sansone, Alberto Raggi, Domenico D’Amico, Frank Andrasik
Published in:
Neurological Sciences
|
Special Issue 1/2019
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Excerpt
Chronic migraine is a difficult condition to treat and few evidence-based treatments have demonstrated their efficacy. Based on the results from a phase III clinical trial program (PREEMPT), onabotulinumtoxin A (OBT-A) has been approved for symptom relief in patients with chronic migraine who have failed, or do not tolerate, oral prophylactic treatments. Even if the results from the clinical studies are encouraging, several aspects of OBT-A use in clinical practice are still controversial and they are the argument of the discussion. Chronic migraine is a problematic condition and always associated with high levels of disability, lessened quality of life and high catastrophizing attitude [
1,
2]. …