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01-07-2020 | Osteoarthrosis | Original Article

Impact of thumb osteoarthritis on pain, function, and quality of life: a comparative study between erosive and non-erosive hand osteoarthritis

Authors: Sara Tenti, Fabio Ferretti, Roberto Gusinu, Ines Gallo, Stefano Giannotti, Andrea Pozza, Antonella Fioravanti, Anna Coluccia

Published in: Clinical Rheumatology | Issue 7/2020

Abstract

Objective

The study was aimed to compare the impact of thumb base osteoarthritis (TBOA) on pain, function, and quality of life in patients with erosive or non-erosive hand osteoarthritis (HOA).

Methods

This observational retrospective study included 232 patients: 64 with erosive HOA (EHOA) and concomitant TBOA, 36 with isolated EHOA, 97 with non-erosive HOA (non-EHOA) and TBOA, and 35 with isolated non-EHOA. Hand pain by a visual analogue scale (VAS), Functional Index for Hand Osteoarthritis (FIHOA) score, Health Assessment Questionnaire (HAQ), the Medical Outcomes Study 36-Item Short Form (SF-36), and the possible correlations between VAS and FIHOA with radiological score were assessed.

Results

No differences were found between EHOA with TBOA and isolated EHOA in VAS and FIHOA scores; opposite, there was a significant difference in VAS (p < 0.01) and FIHOA (p < 0.001) between subjects with non-EHOA and TBOA and patients with only non-EHOA. VAS and FIHOA values resulted slightly higher in patients with EHOA and TBOA vs non-EHOA and TBOA; they were significantly more elevated in EHOA and TBOA group compared to isolated non-EHOA (p ≤ 0.001) and in isolated EHOA vs isolated non-EHOA (p < 0.01 and p < 0.001, respectively). HAQ, SF-36 resulted significantly better in isolated non-EHOA patients compared to the other groups. Finally, we observed a significant correlation between FIHOA and all the Kallman scales in EHOA patients with TBOA and between FIHOA and Kallman’s thumb score in non-EHOA-TBOA group.

Conclusions

EHOA has a more severe clinical burden than non-EHOA; the presence of TBOA appeared an important determinant of pain and disability in non-EHOA.

Key Points

• Each subset of HOA can have a different impact on pain and functionality, with EHOA determining more severe effects on hand symptoms and disability than non-EHOA.

• The presence of TBOA appeared an important determinant of pain and disability in non-EHOA, but not in EHOA.

• Our findings support the need for an individualized therapy for each phenotype of hand osteoarthritis.

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Title: Impact of thumb osteoarthritis on pain, function, and quality of life: a comparative study between erosive and non-erosive hand osteoarthritis
Authors: Sara Tenti
Fabio Ferretti
Roberto Gusinu
Ines Gallo
Stefano Giannotti
Andrea Pozza
Antonella Fioravanti
Anna Coluccia
Publication date: 01-07-2020
Publisher: Springer London
Keywords: Osteoarthrosis
Osteoarthrosis
Published in: Clinical Rheumatology / Issue 7/2020
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-020-04982-z

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Abstract

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Methods

Results

Conclusions

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