Expanding the spectrum of spondyloarthritis (SpA): post-streptococcal reactive arthritis (PSRA)-related psoriatic spondyloarthritis (PSpA)

Excerpt

The unifying concept of spondyloarthritis (SpA) was introduced by the group of Wright et al. in 1974 [1, 2] following a series of studies in a group of inflammatory disorders until then considered to be variants of rheumatoid arthritis (RA). It was, however, their own clinical work on psoriatic arthritis (PsA) that led them to formulate their concept of SpA [2]. The basic characteristics that bound the group were the following: (a) absence of rheumatoid factor; (b) absence of subcutaneous nodules; (c) peripheral arthritis; (d) radiologic evidence of sacroiliitis, with or without ankylosing spondylitis (AS); (e) tendency to manifest clinical interrelationships between individual members of the group, particularly psoriasiform skin or nail lesions, ocular, buccal, genitourinary inflammation, or bowel ulceration, erythema nodosum, pyoderma gangrenosum, and thrombophlebitis; and f) familial aggregation. …