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Clinical Rheumatology
Published in: Clinical Rheumatology 2/2016

01-02-2016 | Letter to the Editor

The metastasis-associated protein S100A4 may be a new potential therapeutic target for rheumatoid arthritis

Authors: Wei He, Xiao-Di Xu, Hua Wu

Published in: Clinical Rheumatology | Issue 2/2016

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Excerpt

Dear Editor, …
Literature
1.
Bo GP, Zhou LN, He WF, Luo GX, Jia XF, Gan CJ, Chen GX, Fang YF, Larsen PM, Wu J (2009) Analyses of differential proteome of human synovial fibroblasts obtained from arthritis. Clin Rheumatol 28:191–199CrossRefPubMed
2.
Cerezo LA, Kuncova K, Mann H, Tomcik M, Zamecnik J, Lukanidin E, Neidhart M, Gay S, Grigorian M, Vencovsky J, Senolt L (2011) The metastasis promoting protein S100A4 is increased in idiopathic inflammatory myopathies. Rheumatology (Oxford) 50:1766–1772CrossRef
3.
Cerezo LA, Remakova M, Tomcik M, Gay S, Neidhart M, Lukanidin E, Pavelka K, Grigorian M, Vencovsky J, Senolt L (2014) The metastasis-associated protein S100A4 promotes the inflammatory response of mononuclear cells via the TLR4 signalling pathway in rheumatoid arthritis. Rheumatology (Oxford) 53:1520–1526CrossRef
4.
Erlandsson MC, Forslind K, Andersson SE, Lund A, Bokarewa MI (2012) Metastasin S100A4 is increased in proportion to radiographic damage in patients with RA. Rheumatology (Oxford) 51:932–940CrossRef
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Klingelhofer J, Senolt L, Baslund B, Nielsen GH, Skibshoj I, Pavelka K, Neidhart M, Gay S, Ambartsumian N, Hansen BS, Petersen J, Lukanidin E, Grigorian M (2007) Up-regulation of metastasis-promoting S100A4 (Mts-1) in rheumatoid arthritis: putative involvement in the pathogenesis of rheumatoid arthritis. Arthritis Rheum 56:779–789CrossRefPubMed
7.
Nishioku T, Furusho K, Tomita A, Ohishi H, Dohgu S, Shuto H, Yamauchi A, Kataoka Y (2011) Potential role for S100A4 in the disruption of the blood-brain barrier in collagen-induced arthritic mice, an animal model of rheumatoid arthritis. Neuroscience 189:286–292CrossRefPubMed
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Oslejskova L, Grigorian M, Hulejova H, Vencovsky J, Pavelka K, Klingelhofer J, Gay S, Neidhart M, Brabcova H, Suchy D, Senolt L (2009) Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis. Rheumatology (Oxford) 48:1590–1594CrossRef
9.
Senolt L, Grigorian M, Lukanidin E, Simmen B, Michel BA, Pavelka K, Gay RE, Gay S, Neidhart M (2006) S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases. Ann Rheum Dis 65:1645–1648PubMedCentralCrossRefPubMed
Metadata
Title
The metastasis-associated protein S100A4 may be a new potential therapeutic target for rheumatoid arthritis
Authors
Wei He
Xiao-Di Xu
Hua Wu
Publication date
01-02-2016
Publisher
Springer London
Published in
Clinical Rheumatology / Issue 2/2016
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-014-2765-1

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