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01-01-2013 | Case Based Review

Progressive disseminated histoplasmosis in systemic lupus erythematosus—an unusual presentation of acute tenosynovitis and a literature review

Authors: Sian Yik Lim, Kunut Kijsirichareanchai, Richard Winn

Published in: Clinical Rheumatology | Issue 1/2013

Abstract

Progressive disseminated histoplasmosis is a disease where Histoplasma capsulatum affects multiple organs due to the inability of host cellular immunity to control the infection. Progressive disseminated histoplasmosis mainly involves the bone marrow, liver, and lungs. We report an unusual initial presentation of progressive disseminated histoplasmosis presenting as acute tenosynovitis in a systemic lupus erythematosus (SLE) patient. This report highlights the point that H. capsulatum may present as focal lesions and a high level of suspicion is needed to make the diagnosis, especially in SLE patients. We specifically reviewed reported cases of progressive disseminated histoplasmosis in SLE patients, and a review of the literature is presented.

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Title: Progressive disseminated histoplasmosis in systemic lupus erythematosus—an unusual presentation of acute tenosynovitis and a literature review
Authors: Sian Yik Lim
Kunut Kijsirichareanchai
Richard Winn
Publication date: 01-01-2013
Publisher: Springer-Verlag
Published in: Clinical Rheumatology / Issue 1/2013
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-012-2102-5

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