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Published in: Clinical Rheumatology 7/2011

01-07-2011 | Original Article

Prevalence of hyperuricemia in Bangkok population

Authors: Somchai Uaratanawong, S. Suraamornkul, S. Angkeaw, R. Uaratanawong

Published in: Clinical Rheumatology | Issue 7/2011

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Abstract

To investigate the prevalence of hyperuricemia in general Thai population and to evaluate its association with metabolic syndrome. A total of 1,945 subjects who sought for routine annual health checkup in our hospital from 1 October 2009 to 31 March 2010 were enrolled into the study. Inclusion criteria were healthy individuals, aged ≥35 years old, and lived in Bangkok for over 10 years. Data of general health status, age, gender, history of alcoholic consumption, body weight, height, and waist circumference were obtained by an interview-structured questionnaire. Fasting blood sample was collected from each subject early in the morning for uric acid, total cholesterol, high density lipoprotein cholesterol, triglycerides, and glucose levels. The prevalence of hyperuricemia in our study population was 24.4%, being significantly more common in men than women (59% vs. 11%, p < 0.001). The condition was also associated with various features of high body mass index or waist circumference, alcohol consumption, dyslipidemia, and high fasting blood glucose. Metabolic syndrome was found in 35% and 23% of men and women with hyperuricemia; direct relationship between level of uric acid and prevalence of metabolic syndrome was observed. Hyperuricemia is common among Bangkok population in our study. This disorder is frequently associated with metabolic syndrome.
Literature
1.
go back to reference Choi HK, Atkinson K, Karlson EW, Willen WC, Curhan G (2004) Purine-rich foods, dairy and protein intake, and the risk of gout in men. New Eng J Med 350:1003–1007CrossRef Choi HK, Atkinson K, Karlson EW, Willen WC, Curhan G (2004) Purine-rich foods, dairy and protein intake, and the risk of gout in men. New Eng J Med 350:1003–1007CrossRef
2.
go back to reference Krishnan E, Griffith C, Kwoh C (2005) Burden of illness from gout in ambulatory care in the United States. Arhritis Rheum 52:S656 Krishnan E, Griffith C, Kwoh C (2005) Burden of illness from gout in ambulatory care in the United States. Arhritis Rheum 52:S656
3.
go back to reference Arromdee E, Michet CJ, Crowson CS, O’Fallon WM, Gabriel SE (2002) Epidemiology of gout: is the incidence rising? J Rheumatol 29:2403–2406PubMed Arromdee E, Michet CJ, Crowson CS, O’Fallon WM, Gabriel SE (2002) Epidemiology of gout: is the incidence rising? J Rheumatol 29:2403–2406PubMed
4.
go back to reference Wallace KL, Riedel AA, Joseph-Ridge N, Wortmann R (2004) Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population. J Rheumatol 31:1582–1587PubMed Wallace KL, Riedel AA, Joseph-Ridge N, Wortmann R (2004) Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population. J Rheumatol 31:1582–1587PubMed
6.
go back to reference Klemp P, Stansfied S, Castle B, Robertson M (1997) Gout is on the increase in New Zealand. Ann Rheum Dis 56:22–27PubMedCrossRef Klemp P, Stansfied S, Castle B, Robertson M (1997) Gout is on the increase in New Zealand. Ann Rheum Dis 56:22–27PubMedCrossRef
7.
go back to reference Darmawan J, Valkenburg HA, Muirden KD, Wigley RD (1992) The epidemiology of gout and hyperuricemia in a rural population in Java. J Rheumatol 19:1595–1599PubMed Darmawan J, Valkenburg HA, Muirden KD, Wigley RD (1992) The epidemiology of gout and hyperuricemia in a rural population in Java. J Rheumatol 19:1595–1599PubMed
8.
go back to reference Lee M-S, Lin S-C, Chang H-Y, Lyu L-C, Tsai K-S, Pan W-H (2005) High prevalence of hyperuricemia in elderly Taiwanese. Asia Pac J Clin Nutr 14:285–292PubMed Lee M-S, Lin S-C, Chang H-Y, Lyu L-C, Tsai K-S, Pan W-H (2005) High prevalence of hyperuricemia in elderly Taiwanese. Asia Pac J Clin Nutr 14:285–292PubMed
9.
10.
go back to reference Campion EW, Glynn RJ, deLabry LO (1987) Asymptomatic hyperruricemia: the risks and consequences. Am J Med 82:421–442PubMedCrossRef Campion EW, Glynn RJ, deLabry LO (1987) Asymptomatic hyperruricemia: the risks and consequences. Am J Med 82:421–442PubMedCrossRef
11.
go back to reference Grundy SM (2007) Metabolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab 92:399–404PubMedCrossRef Grundy SM (2007) Metabolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab 92:399–404PubMedCrossRef
12.
go back to reference Yoo TW, Sung KC, Shin HS, Kim BS, Kang JH et al (2005) Relationship between serum uric acid concentration and insulin resistance and metabolic syndrome. Circ J 69:928–933PubMedCrossRef Yoo TW, Sung KC, Shin HS, Kim BS, Kang JH et al (2005) Relationship between serum uric acid concentration and insulin resistance and metabolic syndrome. Circ J 69:928–933PubMedCrossRef
13.
go back to reference Myers A, Epstein FH, Dodge HJ, Mikkelsen WM (1968) The relation of serum uric acid to risk factors in coronary heart disease. Am J Med 45:520–528PubMedCrossRef Myers A, Epstein FH, Dodge HJ, Mikkelsen WM (1968) The relation of serum uric acid to risk factors in coronary heart disease. Am J Med 45:520–528PubMedCrossRef
14.
go back to reference Iwashima Y, Horio T, Kamide K, Rakugi H, Ogihara T, Kawano Y (2006) Uric acid, left ventricular mass index, and risk of cardiovascular disease in essential hypertension. Hypertension 47:195–202PubMedCrossRef Iwashima Y, Horio T, Kamide K, Rakugi H, Ogihara T, Kawano Y (2006) Uric acid, left ventricular mass index, and risk of cardiovascular disease in essential hypertension. Hypertension 47:195–202PubMedCrossRef
15.
go back to reference Abbbott RD, Brand FN, Kannel WB, Castelli WP (1988) Gout and coronary heart disease: the Framingham study. J Clin Epidemiol 41:237–242CrossRef Abbbott RD, Brand FN, Kannel WB, Castelli WP (1988) Gout and coronary heart disease: the Framingham study. J Clin Epidemiol 41:237–242CrossRef
16.
go back to reference Sundstrom J, Sullivan L, D’Agostino RB, Levy D, Kannel WB, Vasan RS (2005) Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence. Hypertension 45:28–33PubMed Sundstrom J, Sullivan L, D’Agostino RB, Levy D, Kannel WB, Vasan RS (2005) Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence. Hypertension 45:28–33PubMed
17.
go back to reference Krishnan E, Kwoh K, Schumacher HR, Kuller L (2007) Hypertension and incidence of hypertension among men without metabolic syndrome. Hypertension 49:298–303PubMedCrossRef Krishnan E, Kwoh K, Schumacher HR, Kuller L (2007) Hypertension and incidence of hypertension among men without metabolic syndrome. Hypertension 49:298–303PubMedCrossRef
18.
go back to reference Lee J, Sparrow D, Vokonas PS, Landsberg L, Weiss ST (1995) Uric acid and coronary heart disease risk: evidence for a role of uric acid in the obesity-insulin resistance syndrome. the normative aging study. Am J Epidemiol 142:288–294PubMed Lee J, Sparrow D, Vokonas PS, Landsberg L, Weiss ST (1995) Uric acid and coronary heart disease risk: evidence for a role of uric acid in the obesity-insulin resistance syndrome. the normative aging study. Am J Epidemiol 142:288–294PubMed
19.
go back to reference Himmelmann A, Kjeldsen SE, Hedner T (2003) Recent hypertension guidelines: JNC-7 and ESH/ESC. Blood Press 12:196–197PubMedCrossRef Himmelmann A, Kjeldsen SE, Hedner T (2003) Recent hypertension guidelines: JNC-7 and ESH/ESC. Blood Press 12:196–197PubMedCrossRef
20.
go back to reference World Health Organization (1998) Report of a WHO consultation on obesity. obesity: preventing and managing the global epidemic. Geneva: World Health Organization World Health Organization (1998) Report of a WHO consultation on obesity. obesity: preventing and managing the global epidemic. Geneva: World Health Organization
21.
go back to reference Alberti KGM, Zimmer P, Shaw J (2006) Metabolic syndrome: a new world-wide definition. a consensus statement from the International Diabetes Federation. Diabet Med 23:469–480PubMedCrossRef Alberti KGM, Zimmer P, Shaw J (2006) Metabolic syndrome: a new world-wide definition. a consensus statement from the International Diabetes Federation. Diabet Med 23:469–480PubMedCrossRef
22.
go back to reference Nan H, Qiao Q, Dong Y, Gao W, Tang B, Qian R et al (2006) The prevalence of hyperuricemia in a population o f the coastal city of Qingdao, China. J Rheumato l33:1346–1350 Nan H, Qiao Q, Dong Y, Gao W, Tang B, Qian R et al (2006) The prevalence of hyperuricemia in a population o f the coastal city of Qingdao, China. J Rheumato l33:1346–1350
23.
go back to reference Lohsoonthorn V, Dhanamun B, Williams MA (2006) Prevalence of hyperuricemia and its relationship with metabolic syndrome in Thai adults receiving annual health exams. Arch Med Res 37:883–889PubMedCrossRef Lohsoonthorn V, Dhanamun B, Williams MA (2006) Prevalence of hyperuricemia and its relationship with metabolic syndrome in Thai adults receiving annual health exams. Arch Med Res 37:883–889PubMedCrossRef
24.
go back to reference Lin KC, Lin HY, Chou P (2000) Community based epidemiological study on hyperuricemia and gout in Kin-Hu, Kinmen. J Rheumatol 27:1045–1050PubMed Lin KC, Lin HY, Chou P (2000) Community based epidemiological study on hyperuricemia and gout in Kin-Hu, Kinmen. J Rheumatol 27:1045–1050PubMed
25.
go back to reference Gordon T, Kannel WB (1983) Drinking and its relation to smoking, BP, blood lipids, and uric acid. the Framingham study. Arch Int Med 143:1366–1374CrossRef Gordon T, Kannel WB (1983) Drinking and its relation to smoking, BP, blood lipids, and uric acid. the Framingham study. Arch Int Med 143:1366–1374CrossRef
26.
go back to reference Choi HK, Curhan G (2004) Beer, liquor and wine consumption and serum uric acid level: the third National Health and Nutrition Examination Survey. Arthritis Rheum 51:1023–1029PubMedCrossRef Choi HK, Curhan G (2004) Beer, liquor and wine consumption and serum uric acid level: the third National Health and Nutrition Examination Survey. Arthritis Rheum 51:1023–1029PubMedCrossRef
27.
go back to reference Choi HK, Liu S, Curhan G (2005) Intake of purine-rich foods, protein and dairy products and relationship to serum levels of uric acid: the third National Health and Nutrition Examination Survey. Arthritis Rheum 52:283–289PubMedCrossRef Choi HK, Liu S, Curhan G (2005) Intake of purine-rich foods, protein and dairy products and relationship to serum levels of uric acid: the third National Health and Nutrition Examination Survey. Arthritis Rheum 52:283–289PubMedCrossRef
28.
go back to reference Choi JW, Ford ES, Gao X, Choi HK (2008) Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the third National Health and Nutrition Examination Survey. Arthritis Rheum 59:109–116PubMedCrossRef Choi JW, Ford ES, Gao X, Choi HK (2008) Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the third National Health and Nutrition Examination Survey. Arthritis Rheum 59:109–116PubMedCrossRef
29.
go back to reference Yamamoto T, Moriwaki Y, Agbedana OE, Takahashi S, Suda M, Higashino K (1994) Impaired lipoprotein metabolismin patients with primary gout: influence of alcohol intake and body weight. Br J Rheumatol 33:731–734PubMedCrossRef Yamamoto T, Moriwaki Y, Agbedana OE, Takahashi S, Suda M, Higashino K (1994) Impaired lipoprotein metabolismin patients with primary gout: influence of alcohol intake and body weight. Br J Rheumatol 33:731–734PubMedCrossRef
30.
go back to reference Vuorinen-Markkola H, Yki-Jarvinen H (1994) Hyperuricemia and insulin resistance. J Clin Endocrinol Metab 78:25–29PubMedCrossRef Vuorinen-Markkola H, Yki-Jarvinen H (1994) Hyperuricemia and insulin resistance. J Clin Endocrinol Metab 78:25–29PubMedCrossRef
31.
go back to reference Rathmann W, Funkhouser E, Dyer AR, Roseman JM (1998) Relations of hyperuricemia with the various components of the insulin resistance syndrome in young black and white adults: the CARDIA study. coronary artery risk development in young adults. Annuals Epidemiol 8:250–261CrossRef Rathmann W, Funkhouser E, Dyer AR, Roseman JM (1998) Relations of hyperuricemia with the various components of the insulin resistance syndrome in young black and white adults: the CARDIA study. coronary artery risk development in young adults. Annuals Epidemiol 8:250–261CrossRef
32.
go back to reference Choi HK, Atkinson K, Karlson EW, Curhan G (2005) Obesity, weight change, hypertension, diuretic use, and risk of gout in men. Arch Intern Med 165:742–748PubMedCrossRef Choi HK, Atkinson K, Karlson EW, Curhan G (2005) Obesity, weight change, hypertension, diuretic use, and risk of gout in men. Arch Intern Med 165:742–748PubMedCrossRef
33.
34.
go back to reference Masuo K, Kawaguchi H, Mikami H, Ogihara T, Tuck ML (2003) Serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevation. Hypertension 42:474–480PubMedCrossRef Masuo K, Kawaguchi H, Mikami H, Ogihara T, Tuck ML (2003) Serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevation. Hypertension 42:474–480PubMedCrossRef
35.
go back to reference Jordan KM, Cameron JS, Snaith M, Zhang W, Doherty M, Seckl J et al (2007) British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of gout. Rheumatol Oxf 46:1372–1374CrossRef Jordan KM, Cameron JS, Snaith M, Zhang W, Doherty M, Seckl J et al (2007) British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of gout. Rheumatol Oxf 46:1372–1374CrossRef
36.
go back to reference Zhang W, Doherty M, Pascual E, Bardin T, Barskova V, Conaghan P et al (2006) EULAR evidenced based recommendations for gout. Part II: management. report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 65:1312–1324PubMedCrossRef Zhang W, Doherty M, Pascual E, Bardin T, Barskova V, Conaghan P et al (2006) EULAR evidenced based recommendations for gout. Part II: management. report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 65:1312–1324PubMedCrossRef
Metadata
Title
Prevalence of hyperuricemia in Bangkok population
Authors
Somchai Uaratanawong
S. Suraamornkul
S. Angkeaw
R. Uaratanawong
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Clinical Rheumatology / Issue 7/2011
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-011-1699-0

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