Published in:
01-04-2007 | Case Report
Endocarditis associated with antineutrophil cytoplasmic antibodies: a case report and review of the literature
Authors:
Julio A. Chirinos, Vicente F. Corrales-Medina, Santiago Garcia, Daniel M. Lichtstein, Alan L. Bisno, Simon Chakko
Published in:
Clinical Rheumatology
|
Issue 4/2007
Login to get access
Abstract
We report a case of subacute bacterial endocarditis associated with small vessel vasculitis and a strongly positive cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) test. It is important to recognize this cause of positive c-ANCA because infectious endocarditis may closely mimic the clinical manifestations of ANCA-associated vasculitides such as Wegener granulomatosis or microscopic polyangiitis. Furthermore, ANCA-associated vasculitis may result in noninfectious endocarditis, which may be confused with bacterial endocarditis. In this paper, we review reported cases of ANCA-positive bacterial endocarditis and compare them to the reported cases of ANCA-associated idiopathic vasculitis with endocardial compromise.