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Clinical Rheumatology
Published in: Clinical Rheumatology 4/2006

01-07-2006 | Brief Report

Renal amyloidosis: an uncommon complication of juvenile idiopathic arthritis

Authors: Carolina Duarte, Clara Gomes, A Jorge Correia, Manuel Salgado

Published in: Clinical Rheumatology | Issue 4/2006

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Abstract

A 9-year-old girl presented with systemic-onset juvenile idiopathic arthritis, diagnosed at 3.5 of age and which was difficult to control despite several therapeutic trials. Five years after diagnosis of juvenile idiopathic arthritis, nephrotic proteinuria was noticed. Renal biopsy confirmed the diagnosis of amyloidosis, and chlorambucil was initiated, with general improvement of the disease and reduction of proteinuria.
Literature
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David J (1991) Amyloidosis in juvenile chronic arthritis. Clin Exp Rheumatol 9:73−78PubMed
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Woo P (1992) Amyloidosis in pediatric rheumatic diseases. J Rheumatol Suppl 35:10−16PubMed
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Grateau G (2003) Musculoskeletal disorders in secondary amyloidosis and hereditary fevers. Best Pract Res Clin Rheumatol 17:929−944CrossRefPubMed
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Elises JS, Griffiths PD, Hocking MD, Taylor CM, White RH (1988) Simplified quantification of urinary protein excretion in children. Clin Nephrol 30:225−229PubMed
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Prieur AM (2000) Formes systémiques d'arthrite juvénile idiopatique. Aspects évolutifs. Presse Med 29:503−509PubMed
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David J, Vouyiouka O, Ansell BM, Hall A, Woo P (1993) Amyloidosis in juvenile chronic arthritis: a morbidity and mortality study. Clin Exp Rheumatol 11:85−90PubMed
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Hawkins PN et al (1993) Serum amyloid P component scintigraphy and turnover studies for diagnosis and quantitative monitoring of AA amyloidosis in juvenile rheumatoid arthritis. Arthritis Rheum 36:842−851PubMedCrossRef
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Savolainen HA (1999) Chlorambucil in severe juvenile chronic arthritis: longterm followup with special reference to amyloidosis. J Rheumatol 26:898−903PubMed
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Robles NR, Roncero F, Arrobas M, Vega JLA, Casado ES (1999) Tratamiento con clorambucilo de la amiloidosis renal secundaria a artritis reumatoide. Estudio de 6 casos. Med Clin 113:456−458
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Metadata
Title
Renal amyloidosis: an uncommon complication of juvenile idiopathic arthritis
Authors
Carolina Duarte
Clara Gomes
A Jorge Correia
Manuel Salgado
Publication date
01-07-2006
Publisher
Springer-Verlag
Published in
Clinical Rheumatology / Issue 4/2006
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-005-0048-6

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