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01-02-2019 | Original Article

Early repair of ventral incisional hernia may improve quality of life after surgery for abdominal malignancy: a prospective observational cohort study

Authors: M. P. Feng, R. B. Baucom, K. K. Broman, D. A. Harris, M. D. Holzman, L.-C. Huang, J. L. Kaiser, S. L. Kavalukas, O. O. Oyefule, S. E. Phillips, B. K. Poulose, R. A. Pierce

Published in: Hernia | Issue 1/2019

Abstract

Purpose

Recent work has shown that over 40% of patients undergoing surgery for abdominal malignancy develop ventral incisional hernias (VIH) within 2 years. We hypothesized that early repair of VIH for cancer survivors could improve long-term quality of life (QoL).

Methods

All patients presenting with a history of surgery for abdominal malignancy and a VIH were prospectively enrolled. QoL was assessed at baseline and 3-, 6-, 12-, 18-, and 24-month follow-up using abdominal wall-specific (HerQLes) and cancer-specific (FACT-G) instruments. At the study’s conclusion, patients were divided into 2 groups—those that underwent VIH repair during the study’s course (Repair Group) and those that did not (Control Group). Categorical variables were analyzed using Pearson’s Chi-square and continuous variables with Wilcoxon rank sum test.

Results

Eighty-four patients were enrolled. Overall, 46 patients (55%) underwent VIH repair, with 36 repairs (78%) occurring within 3 months of initial evaluation. Sixty-six (79%) had complete 1-year follow-up data, and 30 (36%) had 2-year data, with a median follow-up duration of 15.6 months. At baseline, both groups were similar with respect to demographics, cancer stage, and HerQLes/FACT-G scores. Compared to the Controls, the Repair Group showed greater improvements over baseline HerQLes Summary Scores at the 3-, 6-, 12-, and 18-month time points (median increase, 37 vs. 26 points), and in FACT-G total scores at the 3-, 6-, and 12-month time points (median increase, 6 vs. 4 points).

Conclusions

Repair of VIH after surgery for abdominal malignancy may improve abdominal wall-specific and cancer-specific QoL, making post-resection abdominal wall reconstruction an important aspect of cancer survivorship.

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Title: Early repair of ventral incisional hernia may improve quality of life after surgery for abdominal malignancy: a prospective observational cohort study
Authors: M. P. Feng
R. B. Baucom
K. K. Broman
D. A. Harris
M. D. Holzman
L.-C. Huang
J. L. Kaiser
S. L. Kavalukas
O. O. Oyefule
S. E. Phillips
B. K. Poulose
R. A. Pierce
Publication date: 01-02-2019
Publisher: Springer Paris
Published in: Hernia / Issue 1/2019
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI: https://doi.org/10.1007/s10029-018-1863-4

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Early repair of ventral incisional hernia may improve quality of life after surgery for abdominal malignancy: a prospective observational cohort study

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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