Skip to main content
Top
Published in: Oral and Maxillofacial Surgery 2/2020

01-06-2020 | Acute Myeloid Leukemia | Case Report

Myeloid sarcoma on the temporal region before the onset of the acute myeloid leukemia: an extremely rare case report

Authors: Yuri Slusarenko da Silva, Maria da Graça Naclério-Homem

Published in: Oral and Maxillofacial Surgery | Issue 2/2020

Login to get access

Abstract

Purpose

Myeloid sarcoma (MS) is a rare malignant tumor that arises outside the bone marrow and usually occurs concomitantly or after the acute myeloid leukemia (AML). The aim of the present study is to report an extremely rare case of a patient with an MS arising in the maxillofacial region before the onset of AML to serve as a guide on how to conduct the initial assessment and diagnosis of similar cases.

Materials and methods

A 29-year-old healthy man complained of a “swelling on the head,” which was rapidly increasing. He was asymptomatic and never had a previous AML.

Results

The patient presented a large mass on the left temporal region. The computed tomography showed a well-delimited lesion extending from the lateral pterygoid muscle and involving the zygomatic arch and lateral orbital rim. The mass was diagnosed as an MS arising before the onset of the AML.

Conclusion

Masses of a rapid increase in the maxillofacial region should always raise suspicion of being an MS even in asymptomatic patients. Following a protocol of initial assessment and diagnosis will decrease the period between the initial appearance of the MS and effective treatment aimed to prevent or delay the manifestation of leukemia, improving the prognosis and survival of these patients.
Literature
1.
go back to reference Chan ACL, Chan JKC (2009) Hematolymphoid lesions of the head and neck. In: Barner L (ed) Surgical pathology of head and neck, 3rd edn. Informa Health Care, New York, pp 997–1133 Chan ACL, Chan JKC (2009) Hematolymphoid lesions of the head and neck. In: Barner L (ed) Surgical pathology of head and neck, 3rd edn. Informa Health Care, New York, pp 997–1133
2.
go back to reference Meis JM, Butler JJ, Osborne BM, Manning JT (1986) Granulocytic sarcoma in nonleukemic patients. Cancer 58:2697–2709CrossRef Meis JM, Butler JJ, Osborne BM, Manning JT (1986) Granulocytic sarcoma in nonleukemic patients. Cancer 58:2697–2709CrossRef
3.
go back to reference Ishikawa S, Kato Y, Kabasawa T, Yoshioka C, Kitabatake K, Yamakawa M, Ishizawa K, Iino M (2019) A case of myeloid sarcoma of the mandibular gingiva as extramedullary relapse of acute myeloid leukemia. Oral Maxillofac Surg [Epub ahead of print] Ishikawa S, Kato Y, Kabasawa T, Yoshioka C, Kitabatake K, Yamakawa M, Ishizawa K, Iino M (2019) A case of myeloid sarcoma of the mandibular gingiva as extramedullary relapse of acute myeloid leukemia. Oral Maxillofac Surg [Epub ahead of print]
4.
go back to reference Junior NLF, Paves L, Nakanami DM, Seixas MT, Manso PG (2005) Sarcoma granulocítico em órbita: relato de caso. Arq Bras Oftalmol 68:557–560CrossRef Junior NLF, Paves L, Nakanami DM, Seixas MT, Manso PG (2005) Sarcoma granulocítico em órbita: relato de caso. Arq Bras Oftalmol 68:557–560CrossRef
5.
go back to reference Yamashita Y, Isomura N, Hamasaki Y, Goto M (2013) Case of pediatric acute romyelocytic leukemia presenting as extramedullary tumor of the mandible. Head Neck 35:E310–E313PubMed Yamashita Y, Isomura N, Hamasaki Y, Goto M (2013) Case of pediatric acute romyelocytic leukemia presenting as extramedullary tumor of the mandible. Head Neck 35:E310–E313PubMed
6.
go back to reference Raphael J, Valent A, Hanna C, Auger N, Casiraghi O, Ribrag V, De Botton S, Saada V (2014) Myeloid sarcoma of the nasopharynx mimicking an aggressive lymphoma. Head Neck Pathol 8:234–238CrossRef Raphael J, Valent A, Hanna C, Auger N, Casiraghi O, Ribrag V, De Botton S, Saada V (2014) Myeloid sarcoma of the nasopharynx mimicking an aggressive lymphoma. Head Neck Pathol 8:234–238CrossRef
7.
go back to reference Yamauchi K, Yasuda M (2002) Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer 94:1739–1746CrossRef Yamauchi K, Yasuda M (2002) Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer 94:1739–1746CrossRef
8.
go back to reference Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE, Bennett JM (1981) Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer 48:1426–1437CrossRef Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE, Bennett JM (1981) Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer 48:1426–1437CrossRef
9.
go back to reference Campidelli C, Agostinelli C, Stitson R, Pileri SA (2009) Myeloid sarcoma: extramedullary manifestation of myeloid disorders. Am J Clin Pathol 132:426–437CrossRef Campidelli C, Agostinelli C, Stitson R, Pileri SA (2009) Myeloid sarcoma: extramedullary manifestation of myeloid disorders. Am J Clin Pathol 132:426–437CrossRef
10.
go back to reference Pileri AS, Ascani S, Cox MC et al (2007) Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 21:340–350CrossRef Pileri AS, Ascani S, Cox MC et al (2007) Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 21:340–350CrossRef
Metadata
Title
Myeloid sarcoma on the temporal region before the onset of the acute myeloid leukemia: an extremely rare case report
Authors
Yuri Slusarenko da Silva
Maria da Graça Naclério-Homem
Publication date
01-06-2020
Publisher
Springer Berlin Heidelberg
Published in
Oral and Maxillofacial Surgery / Issue 2/2020
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI
https://doi.org/10.1007/s10006-020-00833-y

Other articles of this Issue 2/2020

Oral and Maxillofacial Surgery 2/2020 Go to the issue