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Open Access 01-07-2018 | Original Contribution

Mental disorders and the risk for the subsequent first suicide attempt: results of a community study on adolescents and young adults

Authors: Marcel Miché, Patrizia Denise Hofer, Catharina Voss, Andrea Hans Meyer, Andrew Thomas Gloster, Katja Beesdo-Baum, Roselind Lieb

Published in: European Child & Adolescent Psychiatry | Issue 7/2018

Abstract

Adolescents and young adults represent the high-risk group for first onset of both DSM-IV mental disorders and lifetime suicide attempt (SA). Yet few studies have evaluated the temporal association of prior mental disorders and subsequent first SA in a young community sample. We examined (a) such associations using a broad range of specific DSM-IV mental disorders, (b) the risk of experiencing the outcome due to prior comorbidity, and (c) the proportion of SAs that could be attributed to prior disorders. During a 10-year prospective study, data were gathered from 3021 community subjects, 14–24 years of age at baseline. DSM-IV disorders and SA were assessed with the Munich-Composite International Diagnostic Interview. Cox models with time-dependent covariates were used to estimate the temporal associations of prior mental disorders with subsequent first SA. Most prior mental disorders showed elevated risk for subsequent first SA. Highest risks were associated with posttraumatic stress disorder (PTSD), dysthymia, and nicotine dependence. Comorbidity elevated the risk for subsequent first SA, and the more disorders a subject had, the higher the risk for first SA. More than 90% of SAs in the exposed group could be attributed to PTSD, and over 30% of SAs in the total sample could be attributed to specific phobia. Several DSM-IV disorders increase the risk for first SA in adolescents and young adults. Several promising early intervention targets were observed, e.g., specific phobia, nicotine dependence, dysthymia, and whether a young person is burdened with comorbid mental disorders.

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Title: Mental disorders and the risk for the subsequent first suicide attempt: results of a community study on adolescents and young adults
Authors: Marcel Miché
Patrizia Denise Hofer
Catharina Voss
Andrea Hans Meyer
Andrew Thomas Gloster
Katja Beesdo-Baum
Roselind Lieb
Publication date: 01-07-2018
Publisher: Springer Berlin Heidelberg
Published in: European Child & Adolescent Psychiatry / Issue 7/2018
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI: https://doi.org/10.1007/s00787-017-1060-5

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Mental disorders and the risk for the subsequent first suicide attempt: results of a community study on adolescents and young adults

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

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