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European Child & Adolescent Psychiatry
Published in: European Child & Adolescent Psychiatry 3/2010

01-03-2010 | Review

Genetics of developmental dyslexia

Authors: Thomas S. Scerri, Gerd Schulte-Körne

Published in: European Child & Adolescent Psychiatry | Issue 3/2010

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Abstract

Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration.
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Metadata
Title
Genetics of developmental dyslexia
Authors
Thomas S. Scerri
Gerd Schulte-Körne
Publication date
01-03-2010
Publisher
Springer-Verlag
Published in
European Child & Adolescent Psychiatry / Issue 3/2010
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI
https://doi.org/10.1007/s00787-009-0081-0

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