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Clinical Oral Investigations

Published in:

01-09-2021 | Original Article

The effect of anatomy on osteogenesis after maxillary sinus floor augmentation: a radiographic and histological analysis

Authors: Wenjie Zhou, Feng Wang, Marko Magic, Minjie Zhuang, Jian Sun, Yiqun Wu

Published in: Clinical Oral Investigations | Issue 9/2021

Abstract

Objectives

To assess how anatomy and osteogenesis correlated with results of maxillary sinus floor augmentation (MSFA).

Materials and methods

Patients with partial edentulism and advanced atrophy of the posterior maxillae (≤ 4 mm residual bone height, RBH) underwent MSFA with sole deproteinized bovine bone matrix (DBBM) through a lateral approach. After a 6 to 9-month healing period, bone core biopsies were obtained from the sites of implant insertion for histological evaluation. The correlations between anatomical and histomorphometric variables were analyzed in a multiple regression model.

Results

Forty-nine patients were recruited. One biopsy per patient was obtained from the augmented sinus. Thirty-seven bone core biopsies were intact and met the requirement for histomorphometry analysis. The mean (± standard deviation) percentages of vital bone (VB), remaining DBBM, and non-mineralized tissue were 18.25 ± 4.76%, 27.74 ± 6.68%, and 54.08 ± 6.07%, respectively. No statistically significant correlations were found between RBH and VB% (p = 0.44) or between sinus contour and VB% (p = 0.33). However, there was an inverse correlation between the sinus width (SW) and VB % (SW₁: R² = 0.13, p = 0.03; SW₂: R² = 0.15, p = 0.02).

Conclusions

After a healing period of 6–9 months, wider sinuses augmented with DBBM alone tended to have a lower proportion of new bone formation, while RBH and sinus contour did not appear to affect osteogenesis after MSFA.

Clinical relevance

This study emphasized the effect of anatomy on osteogenesis after MSFA. The result of the study may have an indication to the clinician that SW is a consideration when selecting the bone grafting material and deciding the healing period of MSFA.

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Title: The effect of anatomy on osteogenesis after maxillary sinus floor augmentation: a radiographic and histological analysis
Authors: Wenjie Zhou
Feng Wang
Marko Magic
Minjie Zhuang
Jian Sun
Yiqun Wu
Publication date: 01-09-2021
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 9/2021
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-021-03827-6

At a glance: The STEP trials

Springer Medicine

The effect of anatomy on osteogenesis after maxillary sinus floor augmentation: a radiographic and histological analysis

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

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