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Published in: Clinical Oral Investigations 2/2017

01-03-2017 | Review

Outcomes of implant therapy in patients with a history of aggressive periodontitis. A systematic review and meta-analysis

Authors: Charis Theodoridis, Andreas Grigoriadis, Georgios Menexes, Ioannis Vouros

Published in: Clinical Oral Investigations | Issue 2/2017

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Abstract

Objective

To investigate the outcomes of implant therapy in partially dentate patients treated for aggressive periodontitis (GAgP) in comparison to periodontally healthy (HP) and patients treated for chronic periodontitis (CP) utilizing radiographic and clinical parameters.

Material and methods

An electronic search of databases, supplemented by hand searching, was conducted to identify relevant clinical studies. Sequential screenings at the title, abstract and full-text levels were performed independently and in duplicate. A random effects meta-analysis was conducted and bias corrected bootstrap 95 % confidence intervals were estimated for group comparisons.

Results

The search strategy revealed a total of 899 results. After title screening, abstract scanning, and full-text reading, seven articles fulfilled the inclusion criteria. The 3-year survival rate for CP and HP patients was 100 % while in GAgP subjects, the respective value was 97.98 %; this difference being statistically significant. The 3-year mean marginal bone loss (MBL) was 1.07 mm for the GAgP group, 0.47 mm for the CP group, and 0.69 mm for the HP group. A significant difference between the GAgP and CP groups was identified (p < 0.05). The weighted mean differences of MBL concerning the above groups were also calculated and examined for statistical significance in both 1 and 3 years.

Conclusions

The 3-year survival rate and peri-implant marginal bone loss was found statistically significantly lower in GAgP subjects (SR 97.98 % vs 100 %) in comparison to HP and CP individuals.

Clinical relevance

The outcome of implant therapy in terms of survival rate and marginal bone loss is considered very important for the clinician in decision making when placing implants in patients with a history of aggressive periodontitis.
Literature
1.
go back to reference Jung RE, Zembic A, Pjetursson BE, Zwahlen M, Thoma DS (2012) Systematic review of the survival rate and the incidence of biological, technical, and aesthetic complications of single crowns on implants reported in longitudinal studies with a mean follow-up of 5 years. Clin Oral Implants Res 23(s6):2–21CrossRefPubMed Jung RE, Zembic A, Pjetursson BE, Zwahlen M, Thoma DS (2012) Systematic review of the survival rate and the incidence of biological, technical, and aesthetic complications of single crowns on implants reported in longitudinal studies with a mean follow-up of 5 years. Clin Oral Implants Res 23(s6):2–21CrossRefPubMed
2.
go back to reference Donos N, Laurell L, Mardas N (2012) Hierarchical decisions on teeth vs. implants in the periodontitis-susceptible patient: the modern dilemma. Periodontol 59(1):89–110CrossRef Donos N, Laurell L, Mardas N (2012) Hierarchical decisions on teeth vs. implants in the periodontitis-susceptible patient: the modern dilemma. Periodontol 59(1):89–110CrossRef
3.
go back to reference Albrektsson T, Donos N (2012) Implant survival and complications. The third EAO consensus conference 2012. Clin Oral Implants Res 23(s6):63–65CrossRefPubMed Albrektsson T, Donos N (2012) Implant survival and complications. The third EAO consensus conference 2012. Clin Oral Implants Res 23(s6):63–65CrossRefPubMed
4.
go back to reference Charalampakis G, Rabe P, Leonhardt Å, Dahlén G (2011) A follow-up study of peri-implantitis cases after treatment. J Clin Periodontol 38(9):864–871CrossRefPubMed Charalampakis G, Rabe P, Leonhardt Å, Dahlén G (2011) A follow-up study of peri-implantitis cases after treatment. J Clin Periodontol 38(9):864–871CrossRefPubMed
5.
go back to reference Zitzmann NU, Berglundh T (2008) Definition and prevalence of peri-implant diseases. J Clin Periodontol 35(s8):286–291CrossRefPubMed Zitzmann NU, Berglundh T (2008) Definition and prevalence of peri-implant diseases. J Clin Periodontol 35(s8):286–291CrossRefPubMed
6.
go back to reference Ong CT, Ivanovski S, Needleman IG, Retzepi M, Moles DR, Tonetti MS, Donos N (2008) Systematic review of implant outcomes in treated periodontitis subjects. J Clin Periodontol 35(5):438–462CrossRefPubMed Ong CT, Ivanovski S, Needleman IG, Retzepi M, Moles DR, Tonetti MS, Donos N (2008) Systematic review of implant outcomes in treated periodontitis subjects. J Clin Periodontol 35(5):438–462CrossRefPubMed
7.
go back to reference Sgolastra F, Petrucci A, Severino M, Gatto R, Monaco A (2015) Periodontitis, implant loss and peri-implantitis. A meta-analysis. Clin Oral Implants Res 26(4):e8–16CrossRefPubMed Sgolastra F, Petrucci A, Severino M, Gatto R, Monaco A (2015) Periodontitis, implant loss and peri-implantitis. A meta-analysis. Clin Oral Implants Res 26(4):e8–16CrossRefPubMed
8.
go back to reference Sousa V, Mardas N, Farias B, Petrie A, Needleman I, Spratt D, Donos N (2015) A systematic review of implant outcomes in treated periodontitis patients. Clinical oral implants research Sousa V, Mardas N, Farias B, Petrie A, Needleman I, Spratt D, Donos N (2015) A systematic review of implant outcomes in treated periodontitis patients. Clinical oral implants research
9.
go back to reference Leonhardt Å, Berglundh T, Ericsson I, Dahlén G (1992) Putative periodontal and teeth in pathogens on titanium implants and teeth in experimental gingivitis and periodontitis in beagle dogs. Clin Oral Implants Res 3(3):112–119CrossRefPubMed Leonhardt Å, Berglundh T, Ericsson I, Dahlén G (1992) Putative periodontal and teeth in pathogens on titanium implants and teeth in experimental gingivitis and periodontitis in beagle dogs. Clin Oral Implants Res 3(3):112–119CrossRefPubMed
10.
go back to reference Koyanagi T, Sakamoto M, Takeuchi Y, Maruyama N, Ohkuma M, Izumi Y (2013) Comprehensive microbiological findings in peri-implantitis and periodontitis. J Clin Periodontol 40(3):218–226CrossRefPubMed Koyanagi T, Sakamoto M, Takeuchi Y, Maruyama N, Ohkuma M, Izumi Y (2013) Comprehensive microbiological findings in peri-implantitis and periodontitis. J Clin Periodontol 40(3):218–226CrossRefPubMed
11.
go back to reference Zhuang LF, Watt RM, Mattheos N, Si MS, Lai HC, Lang NP (2016) Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri-implant tissues. Clin Oral Implants Res 27(1):13–21CrossRefPubMed Zhuang LF, Watt RM, Mattheos N, Si MS, Lai HC, Lang NP (2016) Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri-implant tissues. Clin Oral Implants Res 27(1):13–21CrossRefPubMed
12.
go back to reference Belibasakis GN, Charalampakis G, Bostanci N, Stadlinger B (2015) Peri-implant infections of oral biofilm etiology. In: Biofilm-based healthcare-associated Infections. edn. Springer;69–84. Belibasakis GN, Charalampakis G, Bostanci N, Stadlinger B (2015) Peri-implant infections of oral biofilm etiology. In: Biofilm-based healthcare-associated Infections. edn. Springer;69–84.
13.
go back to reference Charalampakis G, Belibasakis GN (2015) Microbiome of peri-implant infections: lessons from conventional, molecular and metagenomic analyses. Virulence 6(3):183–187CrossRefPubMedPubMedCentral Charalampakis G, Belibasakis GN (2015) Microbiome of peri-implant infections: lessons from conventional, molecular and metagenomic analyses. Virulence 6(3):183–187CrossRefPubMedPubMedCentral
14.
go back to reference Mombelli A, Oosten M, Schürch E, Lang N (1987) The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 2(4):145–151CrossRefPubMed Mombelli A, Oosten M, Schürch E, Lang N (1987) The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 2(4):145–151CrossRefPubMed
15.
go back to reference Sachdeo A, Haffajee AD, Socransky SS (2008) Biofilms in the edentulous oral cavity. J Prosthodont 17(5):348–356CrossRefPubMed Sachdeo A, Haffajee AD, Socransky SS (2008) Biofilms in the edentulous oral cavity. J Prosthodont 17(5):348–356CrossRefPubMed
16.
go back to reference de Waal YC, Winkel EG, Meijer HJ, Raghoebar GM, van Winkelhoff AJ (2014) Differences in peri-implant microflora between fully and partially edentulous patients: a systematic review. J Periodontol 85(1):68–82CrossRefPubMed de Waal YC, Winkel EG, Meijer HJ, Raghoebar GM, van Winkelhoff AJ (2014) Differences in peri-implant microflora between fully and partially edentulous patients: a systematic review. J Periodontol 85(1):68–82CrossRefPubMed
17.
go back to reference Bragger U: Maintenance, monitoring, therapy of implant failures. In: Proceedings of the 1st European Workshop on Periodontology London: Quintessence Publishing Co Inc: 1994; 1994: 345–364. Bragger U: Maintenance, monitoring, therapy of implant failures. In: Proceedings of the 1st European Workshop on Periodontology London: Quintessence Publishing Co Inc: 1994; 1994: 345–364.
18.
go back to reference Papaioannou W, Quirynen M, Van Steenberghe D (1996) The influence of periodontitis on the subgingival flora around implants in partially edentulous patients. Clin Oral Implants Res 7(4):405–409CrossRefPubMed Papaioannou W, Quirynen M, Van Steenberghe D (1996) The influence of periodontitis on the subgingival flora around implants in partially edentulous patients. Clin Oral Implants Res 7(4):405–409CrossRefPubMed
19.
go back to reference Susin C, Haas AN, Albandar JM (2014) Epidemiology and demographics of aggressive periodontitis. Periodontol 65(1):27–45CrossRef Susin C, Haas AN, Albandar JM (2014) Epidemiology and demographics of aggressive periodontitis. Periodontol 65(1):27–45CrossRef
20.
go back to reference Armitage GC (1999) Development of a classification system for periodontal diseases and conditions. Annals of periodontology 4(1):1–6CrossRefPubMed Armitage GC (1999) Development of a classification system for periodontal diseases and conditions. Annals of periodontology 4(1):1–6CrossRefPubMed
21.
go back to reference Bullon P, Fioroni M, Goteri G, Rubini C, Battino M (2004) Immunohistochemical analysis of soft tissues in implants with healthy and peri-implantitis condition, and aggressive periodontitis. Clin Oral Implants Res 15(5):553–559CrossRefPubMed Bullon P, Fioroni M, Goteri G, Rubini C, Battino M (2004) Immunohistochemical analysis of soft tissues in implants with healthy and peri-implantitis condition, and aggressive periodontitis. Clin Oral Implants Res 15(5):553–559CrossRefPubMed
22.
go back to reference Boever AL, Boever JA (2006) Early colonization of non-submerged dental implants in patients with a history of advanced aggressive periodontitis. Clin Oral Implants Res 17(1):8–17CrossRefPubMed Boever AL, Boever JA (2006) Early colonization of non-submerged dental implants in patients with a history of advanced aggressive periodontitis. Clin Oral Implants Res 17(1):8–17CrossRefPubMed
23.
go back to reference Quirynen M, Vogels R, Peeters W, Steenberghe D, Naert I, Haffajee A (2006) Dynamics of initial subgingival colonization of ‘pristine’ peri-implant pockets. Clin Oral Implants Res 17(1):25–37CrossRefPubMed Quirynen M, Vogels R, Peeters W, Steenberghe D, Naert I, Haffajee A (2006) Dynamics of initial subgingival colonization of ‘pristine’ peri-implant pockets. Clin Oral Implants Res 17(1):25–37CrossRefPubMed
24.
go back to reference Al-Zahrani MS (2008) Implant therapy in aggressive periodontitis patients: a systematic review and clinical implications. Quintessence Int 39(3):211–215PubMed Al-Zahrani MS (2008) Implant therapy in aggressive periodontitis patients: a systematic review and clinical implications. Quintessence Int 39(3):211–215PubMed
25.
go back to reference Kim KK, Sung HM (2012) Outcomes of dental implant treatment in patients with generalized aggressive periodontitis: a systematic review. The journal of advanced prosthodontics 4(4):210–217CrossRefPubMedPubMedCentral Kim KK, Sung HM (2012) Outcomes of dental implant treatment in patients with generalized aggressive periodontitis: a systematic review. The journal of advanced prosthodontics 4(4):210–217CrossRefPubMedPubMedCentral
26.
go back to reference Karoussis IK, Kotsovilis S, Fourmousis I (2007) A comprehensive and critical review of dental implant prognosis in periodontally compromised partially edentulous patients. Clin Oral Implants Res 18(6):669–679CrossRefPubMed Karoussis IK, Kotsovilis S, Fourmousis I (2007) A comprehensive and critical review of dental implant prognosis in periodontally compromised partially edentulous patients. Clin Oral Implants Res 18(6):669–679CrossRefPubMed
27.
go back to reference Higgins J, Green S (2012) Cochrane handbook for systematic reviews of interventions version 5.1. 0 [updated Mar 2011]. The Cochrane collaboration 2011 Higgins J, Green S (2012) Cochrane handbook for systematic reviews of interventions version 5.1. 0 [updated Mar 2011]. The Cochrane collaboration 2011
28.
go back to reference Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Research methods & reporting—preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement-David Moher and colleagues introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses. BMJ (CR)-print 338(7716):332 Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Research methods & reporting—preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement-David Moher and colleagues introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses. BMJ (CR)-print 338(7716):332
29.
go back to reference Wells G, Shay B, O’Connell D (2009) The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analysis. University of Ottawa, Ottawa Wells G, Shay B, O’Connell D (2009) The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analysis. University of Ottawa, Ottawa
30.
go back to reference Brannick MT, Yang L-Q, Cafri G (2011) Comparison of weights for meta-analysis of r and d under realistic conditions. Organ Res Methods 14(4):587–607CrossRef Brannick MT, Yang L-Q, Cafri G (2011) Comparison of weights for meta-analysis of r and d under realistic conditions. Organ Res Methods 14(4):587–607CrossRef
31.
go back to reference Karkos CD, Menexes GC, Patelis N, Kalogirou TE, Giagtzidis IT, Harkin DW (2014) A systematic review and meta-analysis of abdominal compartment syndrome after endovascular repair of ruptured abdominal aortic aneurysms. J Vasc Surg 59(3):829–842CrossRefPubMed Karkos CD, Menexes GC, Patelis N, Kalogirou TE, Giagtzidis IT, Harkin DW (2014) A systematic review and meta-analysis of abdominal compartment syndrome after endovascular repair of ruptured abdominal aortic aneurysms. J Vasc Surg 59(3):829–842CrossRefPubMed
32.
go back to reference Borenstein MH, Higgins L, Rothstein J (2009) HR. Introduction to meta-analysis. Chichester, England: Wiley doi 2009, 10:9780470743386. Borenstein MH, Higgins L, Rothstein J (2009) HR. Introduction to meta-analysis. Chichester, England: Wiley doi 2009, 10:9780470743386.
33.
go back to reference Gurevitch J, Hedges LV (1999) Statistical issues in ecological meta-analyses. Ecology 80(4):1142–1149CrossRef Gurevitch J, Hedges LV (1999) Statistical issues in ecological meta-analyses. Ecology 80(4):1142–1149CrossRef
34.
go back to reference Monje A, Alcoforado G, Padial-Molina M, Suarez F, Lin GH, Wang HL (2014) Generalized aggressive periodontitis as a risk factor for dental implant failure: a systematic review and meta-analysis. J Periodontol 85(10):1398–1407CrossRefPubMed Monje A, Alcoforado G, Padial-Molina M, Suarez F, Lin GH, Wang HL (2014) Generalized aggressive periodontitis as a risk factor for dental implant failure: a systematic review and meta-analysis. J Periodontol 85(10):1398–1407CrossRefPubMed
35.
go back to reference Adams DC, Gurevitch J, Rosenberg MS (1997) Resampling tests for meta-analysis of ecological data. Ecology 78(4):1277–1283CrossRef Adams DC, Gurevitch J, Rosenberg MS (1997) Resampling tests for meta-analysis of ecological data. Ecology 78(4):1277–1283CrossRef
36.
go back to reference Rosenberg MS, Adams DC, Gurevitch J (2000) MetaWin: statistical software for meta-analysis. Sinauer Associates Sunderland, Massachusetts Rosenberg MS, Adams DC, Gurevitch J (2000) MetaWin: statistical software for meta-analysis. Sinauer Associates Sunderland, Massachusetts
37.
go back to reference Veresoglou SD, Menexes G, Rillig MC (2012) Do arbuscular mycorrhizal fungi affect the allometric partition of host plant biomass to shoots and roots? A meta-analysis of studies from 1990 to 2010. Mycorrhiza 22(3):227–235CrossRefPubMed Veresoglou SD, Menexes G, Rillig MC (2012) Do arbuscular mycorrhizal fungi affect the allometric partition of host plant biomass to shoots and roots? A meta-analysis of studies from 1990 to 2010. Mycorrhiza 22(3):227–235CrossRefPubMed
38.
go back to reference Mengel R, Flores-de-Jacoby L (2005) Implants in patients treated for generalized aggressive and chronic periodontitis: a 3-year prospective longitudinal study. J Periodontol 76(4):534–543CrossRefPubMed Mengel R, Flores-de-Jacoby L (2005) Implants in patients treated for generalized aggressive and chronic periodontitis: a 3-year prospective longitudinal study. J Periodontol 76(4):534–543CrossRefPubMed
39.
go back to reference Mengel R, Flores-de-Jacoby L (2005) Implants in regenerated bone in patients treated for generalized aggressive periodontitis: a prospective longitudinal study. Int J Periodontics Restorative Dent 25(4):331–341PubMed Mengel R, Flores-de-Jacoby L (2005) Implants in regenerated bone in patients treated for generalized aggressive periodontitis: a prospective longitudinal study. Int J Periodontics Restorative Dent 25(4):331–341PubMed
40.
go back to reference Mengel R, Kreuzer G, Lehmann KM, Flores-de-Jacoby L (2007) A telescopic crown concept for the restoration of partially edentulous patients with aggressive generalized periodontitis: a 3-year prospective longitudinal study. Int J Periodontics Restorative Dent 27(3) Mengel R, Kreuzer G, Lehmann KM, Flores-de-Jacoby L (2007) A telescopic crown concept for the restoration of partially edentulous patients with aggressive generalized periodontitis: a 3-year prospective longitudinal study. Int J Periodontics Restorative Dent 27(3)
41.
go back to reference De Boever AL, Quirynen M, Coucke W, Theuniers G, De Boever JA (2009) Clinical and radiographic study of implant treatment outcome in periodontally susceptible and non-susceptible patients: a prospective long-term study. Clin Oral Implants Res 20(12):1341–1350CrossRefPubMed De Boever AL, Quirynen M, Coucke W, Theuniers G, De Boever JA (2009) Clinical and radiographic study of implant treatment outcome in periodontally susceptible and non-susceptible patients: a prospective long-term study. Clin Oral Implants Res 20(12):1341–1350CrossRefPubMed
42.
go back to reference Mengel R, Behle M, Flores-de-Jacoby L (2007) Osseointegrated implants in subjects treated for generalized aggressive periodontitis: 10-year results of a prospective, long-term cohort study. J Periodontol 78(12):2229–2237CrossRefPubMed Mengel R, Behle M, Flores-de-Jacoby L (2007) Osseointegrated implants in subjects treated for generalized aggressive periodontitis: 10-year results of a prospective, long-term cohort study. J Periodontol 78(12):2229–2237CrossRefPubMed
43.
go back to reference Mengel R, Schroder T, Flores-de-Jacoby L (2001) Osseointegrated implants in patients treated for generalized chronic periodontitis and generalized aggressive periodontitis: 3- and 5-year results of a prospective long-term study. J Periodontol 72(8):977–989CrossRefPubMed Mengel R, Schroder T, Flores-de-Jacoby L (2001) Osseointegrated implants in patients treated for generalized chronic periodontitis and generalized aggressive periodontitis: 3- and 5-year results of a prospective long-term study. J Periodontol 72(8):977–989CrossRefPubMed
44.
go back to reference Swierkot K, Lottholz P, Flores-de-Jacoby L, Mengel R (2012) Mucositis, peri-implantitis, implant success, and survival of implants in patients with treated generalized aggressive periodontitis: 3- to 16-year results of a prospective long-term cohort study. J Periodontol 83(10):1213–1225CrossRefPubMed Swierkot K, Lottholz P, Flores-de-Jacoby L, Mengel R (2012) Mucositis, peri-implantitis, implant success, and survival of implants in patients with treated generalized aggressive periodontitis: 3- to 16-year results of a prospective long-term cohort study. J Periodontol 83(10):1213–1225CrossRefPubMed
45.
go back to reference Page RC, Altman LC, Ebersole JL, Vandesteen GE, Dahlberg WH, Williams BL, Osterberg SK (1983) Rapidly progressive periodontitis: a distinct clinical condition. J Periodontol 54(4):197–209CrossRefPubMed Page RC, Altman LC, Ebersole JL, Vandesteen GE, Dahlberg WH, Williams BL, Osterberg SK (1983) Rapidly progressive periodontitis: a distinct clinical condition. J Periodontol 54(4):197–209CrossRefPubMed
46.
go back to reference Albrektsson T, Zarb G, Worthington P, Eriksson A (1986) The long-term efficacy of currently used dental implants: a review and proposed criteria of success. International Journal of Oral & Maxillofacial Implants 1(1). Albrektsson T, Zarb G, Worthington P, Eriksson A (1986) The long-term efficacy of currently used dental implants: a review and proposed criteria of success. International Journal of Oral & Maxillofacial Implants 1(1).
47.
go back to reference Schou S, Holmstrup P, Worthington HV, Esposito M (2006) Outcome of implant therapy in patients with previous tooth loss due to periodontitis. Clin Oral Implants Res 17(Suppl 2):104–123CrossRefPubMed Schou S, Holmstrup P, Worthington HV, Esposito M (2006) Outcome of implant therapy in patients with previous tooth loss due to periodontitis. Clin Oral Implants Res 17(Suppl 2):104–123CrossRefPubMed
48.
go back to reference Safii SH, Palmer RM, Wilson RF (2010) Risk of implant failure and marginal bone loss in subjects with a history of periodontitis: a systematic review and meta-analysis. Clin Implant Dent Relat Res 12(3):165–174PubMed Safii SH, Palmer RM, Wilson RF (2010) Risk of implant failure and marginal bone loss in subjects with a history of periodontitis: a systematic review and meta-analysis. Clin Implant Dent Relat Res 12(3):165–174PubMed
49.
go back to reference Gatti C, Gatti F, Chiapasco M, Esposito M (2008) Outcome of dental implants in partially edentulous patients with and without a history of periodontitis: a 5-year interim analysis of a cohort study. European journal of oral implantology 1(1):45–51PubMed Gatti C, Gatti F, Chiapasco M, Esposito M (2008) Outcome of dental implants in partially edentulous patients with and without a history of periodontitis: a 5-year interim analysis of a cohort study. European journal of oral implantology 1(1):45–51PubMed
50.
go back to reference Roccuzzo M, De Angelis N, Bonino L, Aglietta M (2010) Ten-year results of a three-arm prospective cohort study on implants in periodontally compromised patients. Part 1: implant loss and radiographic bone loss. Clin Oral Implants Res 21(5):490–496CrossRefPubMed Roccuzzo M, De Angelis N, Bonino L, Aglietta M (2010) Ten-year results of a three-arm prospective cohort study on implants in periodontally compromised patients. Part 1: implant loss and radiographic bone loss. Clin Oral Implants Res 21(5):490–496CrossRefPubMed
51.
go back to reference Karoussis I, Salvi G, Heitz-Mayfield L, Brägger U, Hämmerle C, Lang N (2009) History of treated periodontitis and smoking as risks for implant therapy. Int J Oral Maxillofac Implants 24:39–68 Karoussis I, Salvi G, Heitz-Mayfield L, Brägger U, Hämmerle C, Lang N (2009) History of treated periodontitis and smoking as risks for implant therapy. Int J Oral Maxillofac Implants 24:39–68
52.
go back to reference Clementini M, Rossetti P, Penarrocha D, Micarelli C, Bonachela W, Canullo L (2014) Systemic risk factors for peri-implant bone loss: a systematic review and meta-analysis. Int J Oral Maxillofac Surg 43(3):323–334CrossRefPubMed Clementini M, Rossetti P, Penarrocha D, Micarelli C, Bonachela W, Canullo L (2014) Systemic risk factors for peri-implant bone loss: a systematic review and meta-analysis. Int J Oral Maxillofac Surg 43(3):323–334CrossRefPubMed
53.
go back to reference Chrcanovic BR, Albrektsson T, Wennerberg A (2015) Smoking and dental implants: a systematic review and meta-analysis. J Dent 43(5):487–498CrossRefPubMed Chrcanovic BR, Albrektsson T, Wennerberg A (2015) Smoking and dental implants: a systematic review and meta-analysis. J Dent 43(5):487–498CrossRefPubMed
54.
go back to reference Moraschini V (2016) Success of dental implants in smokers and non-smokers: a systematic review and meta-analysis. Int J Oral Maxillofac Surg 45(2):205–215CrossRefPubMed Moraschini V (2016) Success of dental implants in smokers and non-smokers: a systematic review and meta-analysis. Int J Oral Maxillofac Surg 45(2):205–215CrossRefPubMed
55.
go back to reference Bezerra Ferreira JD, Rodrigues JA, Piattelli A, Iezzi G, Gehrke SA, Shibli JA (2015) The effect of cigarette smoking on early osseointegration of dental implants: a prospective controlled study. Clinical Oral Implants Research Bezerra Ferreira JD, Rodrigues JA, Piattelli A, Iezzi G, Gehrke SA, Shibli JA (2015) The effect of cigarette smoking on early osseointegration of dental implants: a prospective controlled study. Clinical Oral Implants Research
Metadata
Title
Outcomes of implant therapy in patients with a history of aggressive periodontitis. A systematic review and meta-analysis
Authors
Charis Theodoridis
Andreas Grigoriadis
Georgios Menexes
Ioannis Vouros
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 2/2017
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-016-2026-6

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