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Clinical Oral Investigations
Published in: Clinical Oral Investigations 8/2016

01-11-2016 | Original Article

The relationship between recurrent aphthous stomatitis, and periodontal disease and Helicobacter Pylori infection

Authors: D. Gülseren, A. Karaduman, D. Kutsal, R. M. Nohutcu

Published in: Clinical Oral Investigations | Issue 8/2016

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Abstract

Objective

Recurrent aphthous stomatitis (RAS) is a common oral mucosal disease with unknown etiology. This cross-sectional study aimed to test the hypothesis that Helicobacter pylori and periodontal disease might play an etiological role in RAS.

Methods

Dental plaque samples obtained from 38 patients with RAS and 43 healthy individuals via periodontal examinations were examined for H. pylori colonization. H. pylori was identified using the rapid urease test (RUT). The periodontal status of the patients and controls was based on the following periodontal parameters: periodontal pocket depth (PPD), the plaque index (PI), the gingival index (GI), and clinical attachment loss (CAL).

Results

RUT results were positive in 34 (89.5 %) of the 38 patients and 24 (55.8 %) of the 43 controls (P = 0.002). There were not any significant differences in mean PPD, PI, GI, or CAL between the patient and control groups (P > 0.05). Mean PPD, PI, GI, and CAL were higher in the RUT-positive RAS patients than in the RUT-negative patients (P > 0.05, for all).

Conclusions

The present findings show that H. pylori might have played an etiological role in RAS and might have caused periodontal disease, but RAS was not associated with any of the periodontal parameters examined in this study.

Clinical relevance

The present study indicates that H. pylori plays a role in the development of RAS, but periodontal diseases have no effect on it. Eradicating H. pylori might be useful to prevent RAS.
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Metadata
Title
The relationship between recurrent aphthous stomatitis, and periodontal disease and Helicobacter Pylori infection
Authors
D. Gülseren
A. Karaduman
D. Kutsal
R. M. Nohutcu
Publication date
01-11-2016
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 8/2016
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-015-1704-0

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