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Clinical Oral Investigations

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01-09-2013 | Original Article

Dentofacial characteristics of patients with rheumatoid arthritis

Authors: Derya Yıldırım, Hakan Türkkahraman, H. Hüseyin Yılmaz, Ahmet Yalçın Güngör, Yunus Ugan

Published in: Clinical Oral Investigations | Issue 7/2013

Abstract

Objectives

The aims of this study are to evaluate the dentofacial morphology of patients with rheumatoid arthritis (RA) and to compare the morphological data with those of healthy age- and sex-matched control subjects.

Methods

Twenty-seven RA patients (mean age, 45.77 ± 8.64 years) and 25 healthy subjects (mean age, 44.80 ± 8.24 years) participated in this prospective study. Clinical and functional evaluations of the RA patients were assessed. The erythrocyte sedimentation rate, C-reactive protein level, rheumatoid factor level, and anti-citrullinated peptide antibodies (ACPA) titers of RA patients were determined, and DAS28 scores were calculated. Linear and angular measurements were performed on cephalometric tracings and condylar erosion was evaluated on lateral panoramic radiographs. Statistical comparison of the two groups was performed with an independent samples t test. Pearson correlation analysis was used to assess the relationship between the clinical and laboratory parameters.

Results

Based on DAS28 scores, no patient with RA was in the remission period, 3 patients had low, 23 had medium, and 1 had high disease activity. Sixteen (59.26 %) patients with RA had positive ACPA titers. Lateral cephalometric radiographs revealed statistically significant difference between the two groups for the measurement of U1–NA (millimeter; p = 0.047), U1–NA (degrees; p = 0.031), L1–NB (degrees; p = 0.030), IMPA (L1–MP; p = 0.001), interincisal angle (U1–L1; degrees; p = 0.022) and midface length (Co–A; millimeter; p = 0.033). A significant positive linear correlation was found between disease duration time and DAS28 scores (r = 0.066, p = 0.040).

Conclusions

Dentoalveolar effects of RA on dentofacial morphology are more significant than the skeletal effects. Future studies with larger sample sizes are required to evaluate the exact effects of RA on dentofacial morphology.

Clinical relevance

Clinicians should consider the fact that RA-associated dentoalveolar changes can be observed and may affect the orthodontic treatment process.

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Title: Dentofacial characteristics of patients with rheumatoid arthritis
Authors: Derya Yıldırım
Hakan Türkkahraman
H. Hüseyin Yılmaz
Ahmet Yalçın Güngör
Yunus Ugan
Publication date: 01-09-2013
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 7/2013
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-012-0861-7

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Dentofacial characteristics of patients with rheumatoid arthritis

Abstract

Objectives

Methods

Results

Conclusions

Clinical relevance

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Clinical relevance

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