Skip to main content
Top
Published in: Clinical Oral Investigations 3/2010

01-06-2010 | Original Article

Peri-implant bone reactions around immediately loaded conical implants with different prosthetic suprastructures: histological and histomorphometrical study on minipigs

Authors: Bartolomeo Assenza, Antonio Scarano, Vittoria Perrotti, Iole Vozza, Alessandro Quaranta, Manlio Quaranta, Adriano Piattelli, Giovanna Iezzi

Published in: Clinical Oral Investigations | Issue 3/2010

Login to get access

Abstract

The aim of this study was to evaluate peri-implant bone reactions around immediately loaded conical implants with metal and acrylic resin prosthetic restorations. Five splinted conical implants were inserted in each hemimandible of six minipigs at the alveolar crest level. Ten implants were inserted in each minipig. All the implants were immediately loaded. The implants were divided into a group with an acrylic resin prosthetic restoration and into another group with a metal prosthetic restoration. No postoperative complications or deaths of the minipigs occurred. All minipigs were killed after 3 months. No implant was lost. A total of 60 implants were retrieved and processed to obtain thin ground sections. Histology and histomorphometry showed the presence of compact, mature bone around all the implants. Bone was in close contact with the implant surface starting from the first or second implant threads. A high quantity of mineralized bone was present around immediately loaded conical, root form implants. No differences in the peri-implant bone response were found in the groups with different prosthetic reconstructions.
Literature
1.
go back to reference Esposito M, Grusovin MG, Willings M, Coulthard P, Worthington HV (2007) The effectiveness of immediate, early, and conventional loading of dental implants: a Cochrane systematic review of randomized controlled clinical trials. Int J Oral Maxillofac Implants 22:893–904PubMed Esposito M, Grusovin MG, Willings M, Coulthard P, Worthington HV (2007) The effectiveness of immediate, early, and conventional loading of dental implants: a Cochrane systematic review of randomized controlled clinical trials. Int J Oral Maxillofac Implants 22:893–904PubMed
2.
go back to reference Schnitman PA, Wohrle PS, Rubenstein JE, DaSilva JD, Wang NH (1997) Ten-year results for Branemark implants immediately loaded with fixed prostheses at implant placement. Int J Oral Maxillofac Implants 12:495–503PubMed Schnitman PA, Wohrle PS, Rubenstein JE, DaSilva JD, Wang NH (1997) Ten-year results for Branemark implants immediately loaded with fixed prostheses at implant placement. Int J Oral Maxillofac Implants 12:495–503PubMed
3.
go back to reference Tarnow DP, Emtiaz S, Classi A (1997) Immediate loading of threaded implants at stage 1 surgery in edentulous arches: ten consecutive case reports with 1- to 5-year data. Int J Oral Maxillofac Implants 12:319–324PubMed Tarnow DP, Emtiaz S, Classi A (1997) Immediate loading of threaded implants at stage 1 surgery in edentulous arches: ten consecutive case reports with 1- to 5-year data. Int J Oral Maxillofac Implants 12:319–324PubMed
4.
go back to reference Piattelli A, Corigliano M, Scarano A, Costigliola G, Paolantonio M (1998) Immediate loading of titanium plasma-sprayed implants: an histologic analysis in monkeys. J Periodontol 69:321–327PubMed Piattelli A, Corigliano M, Scarano A, Costigliola G, Paolantonio M (1998) Immediate loading of titanium plasma-sprayed implants: an histologic analysis in monkeys. J Periodontol 69:321–327PubMed
5.
go back to reference Romanos GE, Toh CG, Siar CH, Swaminathan D (2002) Histologic and histomorphometric evaluation of peri-implant bone subjected to immediate loading: an experimental study with Macaca fascicularis. Int J Oral Maxillofac Implants 17:44–51PubMed Romanos GE, Toh CG, Siar CH, Swaminathan D (2002) Histologic and histomorphometric evaluation of peri-implant bone subjected to immediate loading: an experimental study with Macaca fascicularis. Int J Oral Maxillofac Implants 17:44–51PubMed
6.
go back to reference Zubery Y, Bichacho N, Moses O, Tal H (1999) Immediate loading of modular transitional implants: a histologic and histomorphometric study in dogs. Int J Periodontics Restorative Dent 19:343–353PubMed Zubery Y, Bichacho N, Moses O, Tal H (1999) Immediate loading of modular transitional implants: a histologic and histomorphometric study in dogs. Int J Periodontics Restorative Dent 19:343–353PubMed
7.
go back to reference Ledermann PD, Schenk RK, Buser D (1998) Long-lasting osseointegration of immediately loaded, bar-connected TPS screws after 12 years of function: a histologic case report of a 95-year-old patient. Int J Periodontics Restorative Dent 18:552–563PubMed Ledermann PD, Schenk RK, Buser D (1998) Long-lasting osseointegration of immediately loaded, bar-connected TPS screws after 12 years of function: a histologic case report of a 95-year-old patient. Int J Periodontics Restorative Dent 18:552–563PubMed
8.
go back to reference Proussaefs P, Lozada JL (2002) Evaluation of two vitallium blade-form implants retrieved after 13 to 21 years of function: a clinical report. J Prosthet Dent 87:412–415CrossRefPubMed Proussaefs P, Lozada JL (2002) Evaluation of two vitallium blade-form implants retrieved after 13 to 21 years of function: a clinical report. J Prosthet Dent 87:412–415CrossRefPubMed
9.
go back to reference Neugebauer J, Traini T, Thams U, Piattelli A, Zöller JE (2006) Peri-implant bone organization under immediate loading state. Circularly polarized light analyses: a minipig study. J Periodontol 77:152–160CrossRefPubMed Neugebauer J, Traini T, Thams U, Piattelli A, Zöller JE (2006) Peri-implant bone organization under immediate loading state. Circularly polarized light analyses: a minipig study. J Periodontol 77:152–160CrossRefPubMed
10.
go back to reference Albrektsson T, Brånemark P-I, Hasson HA, Lindstrom J (1981) Osseointegrated titanium implants. Requirements for ensuring a long-lasting direct bone to implant anchorage in man. Acta Orthop Scand 52:155–170PubMedCrossRef Albrektsson T, Brånemark P-I, Hasson HA, Lindstrom J (1981) Osseointegrated titanium implants. Requirements for ensuring a long-lasting direct bone to implant anchorage in man. Acta Orthop Scand 52:155–170PubMedCrossRef
11.
go back to reference Büchter A, Kleinheinz J, Wiesmann HP, Seper L, Joos U, Meyer U (2004) Peri-implant bone formation around cylindrical and conical implant systems. Mund Kiefer Gesichtschir 8:282–288CrossRefPubMed Büchter A, Kleinheinz J, Wiesmann HP, Seper L, Joos U, Meyer U (2004) Peri-implant bone formation around cylindrical and conical implant systems. Mund Kiefer Gesichtschir 8:282–288CrossRefPubMed
12.
go back to reference Joos U, Vollmer D, Kleinheinz J (2000) Effect of implant geometry on strain distribution in peri-implant bone. Mund Kiefer Gesichtschir 4:143–147CrossRefPubMed Joos U, Vollmer D, Kleinheinz J (2000) Effect of implant geometry on strain distribution in peri-implant bone. Mund Kiefer Gesichtschir 4:143–147CrossRefPubMed
13.
go back to reference Nordin T, Jonsson G, Nelvig P, Rasmusson L (1998) The use of a cortical fixture design for fixed partial prostheses. A preliminary report. Clin Oral Implants Res 9:343–347CrossRefPubMed Nordin T, Jonsson G, Nelvig P, Rasmusson L (1998) The use of a cortical fixture design for fixed partial prostheses. A preliminary report. Clin Oral Implants Res 9:343–347CrossRefPubMed
14.
go back to reference Sakoh J, Wahlmann U, Stender E, Al-Nawas B, Wagner W (2006) Primary stability of a conical implant and a hybrid cylindric screw-type implant in vitro. Int J Oral Maxillofac Implants 21:560–566PubMed Sakoh J, Wahlmann U, Stender E, Al-Nawas B, Wagner W (2006) Primary stability of a conical implant and a hybrid cylindric screw-type implant in vitro. Int J Oral Maxillofac Implants 21:560–566PubMed
15.
go back to reference Quaresma SE, Cury PR, Sendyk WR, Sendyk C (2008) A finite element analysis of two different dental implants: stress distribution in the prosthesis, abutment, implant, and supporting bone. J Oral Implantol 34:1–6CrossRefPubMed Quaresma SE, Cury PR, Sendyk WR, Sendyk C (2008) A finite element analysis of two different dental implants: stress distribution in the prosthesis, abutment, implant, and supporting bone. J Oral Implantol 34:1–6CrossRefPubMed
16.
go back to reference Wang S, Liu Y, Fang D, Shi S (2007) The miniature pig: a useful large animal model for dental and orofacial research. Oral Dis 13:530–537CrossRefPubMed Wang S, Liu Y, Fang D, Shi S (2007) The miniature pig: a useful large animal model for dental and orofacial research. Oral Dis 13:530–537CrossRefPubMed
17.
go back to reference Nkenke E, Lehner B, Fenner M et al (2005) Immediate versus delayed loading of dental implants in the maxillae of minipigs: follow-up of implant stability and implant failures. Int J Oral Maxillofac Implants 20:39–47PubMed Nkenke E, Lehner B, Fenner M et al (2005) Immediate versus delayed loading of dental implants in the maxillae of minipigs: follow-up of implant stability and implant failures. Int J Oral Maxillofac Implants 20:39–47PubMed
18.
go back to reference Buchter A, Kleinheinz J, Wiesmann HP et al (2005) Biological and biomechanical evaluation of bone remodelling and implant stability after using an osteotome technique. Clin Oral Implants Res 16:1–8PubMed Buchter A, Kleinheinz J, Wiesmann HP et al (2005) Biological and biomechanical evaluation of bone remodelling and implant stability after using an osteotome technique. Clin Oral Implants Res 16:1–8PubMed
19.
go back to reference Büchter A, Joos U, Wiesmann HP, Seper L, Meyer U (2006) Biological and biomechanical evaluation of interface reaction at conical screw-type implants. Head Face Med 2(1):5CrossRefPubMed Büchter A, Joos U, Wiesmann HP, Seper L, Meyer U (2006) Biological and biomechanical evaluation of interface reaction at conical screw-type implants. Head Face Med 2(1):5CrossRefPubMed
20.
go back to reference Joos U, Büchter A, Wiesmann HP, Meyer U (2005) Strain driven fast osseointegration of implants. Head Face Med 1:1–6CrossRef Joos U, Büchter A, Wiesmann HP, Meyer U (2005) Strain driven fast osseointegration of implants. Head Face Med 1:1–6CrossRef
21.
go back to reference Wurzler KK, Heisterkamp M, Bohm H, Kubler NR, Sebald W, Reuther JF (2004) Mandibular reconstruction with autologous bone and osseoinductive implant in the Gottingen minipig. Mund Kiefer Gesichtschir 8:75–82CrossRefPubMed Wurzler KK, Heisterkamp M, Bohm H, Kubler NR, Sebald W, Reuther JF (2004) Mandibular reconstruction with autologous bone and osseoinductive implant in the Gottingen minipig. Mund Kiefer Gesichtschir 8:75–82CrossRefPubMed
22.
go back to reference Laiblin C, Jaeschke G (1979) Clinical study of bone and muscle metabolism under stress conditions in the Goettingen minipig—an experimental study. Berl Munch Tierarztl Wochenschr 92:124–128PubMed Laiblin C, Jaeschke G (1979) Clinical study of bone and muscle metabolism under stress conditions in the Goettingen minipig—an experimental study. Berl Munch Tierarztl Wochenschr 92:124–128PubMed
23.
go back to reference Albrektsson T, Johansson C (2001) Osteoinduction, osteoconduction and osseointegration. Eur Spine J 10:96–101CrossRef Albrektsson T, Johansson C (2001) Osteoinduction, osteoconduction and osseointegration. Eur Spine J 10:96–101CrossRef
24.
go back to reference Hürzeler MB, Quiñones CR, Schüpbach P, Vlassis JM, Strub JR, Caffesse RG (1995) Influence of the suprastructure on the peri-implant tissues in beagle dogs. Clin Oral Implants Res 6:139–148CrossRefPubMed Hürzeler MB, Quiñones CR, Schüpbach P, Vlassis JM, Strub JR, Caffesse RG (1995) Influence of the suprastructure on the peri-implant tissues in beagle dogs. Clin Oral Implants Res 6:139–148CrossRefPubMed
25.
go back to reference Misch CE (2005) Dental implant prosthetics. Elsevier Mosby, St. Louis, USA, pp 502–503 Misch CE (2005) Dental implant prosthetics. Elsevier Mosby, St. Louis, USA, pp 502–503
26.
go back to reference Brunski JB, Puleo DA, Nanci A (2000) Biomaterials and biomechanics of oral and maxillofacial implants: current status and future developments. Int J Oral Maxillofac Implants 15(1):15–46PubMed Brunski JB, Puleo DA, Nanci A (2000) Biomaterials and biomechanics of oral and maxillofacial implants: current status and future developments. Int J Oral Maxillofac Implants 15(1):15–46PubMed
27.
go back to reference Davies SJ, Gray RM, McCord JF (2001) Good occlusal practice in removable prosthodontics. Br Dent J 191(9):491–494 497–502CrossRefPubMed Davies SJ, Gray RM, McCord JF (2001) Good occlusal practice in removable prosthodontics. Br Dent J 191(9):491–494 497–502CrossRefPubMed
28.
go back to reference Meyer U, Vollmer D, Bourauel C, Joos U (2001) Sensitivity analysis of bone geometries around oral implants upon bone loading using finite element method. Comput Methods Biomech Biomed Eng 3:553–559 Meyer U, Vollmer D, Bourauel C, Joos U (2001) Sensitivity analysis of bone geometries around oral implants upon bone loading using finite element method. Comput Methods Biomech Biomed Eng 3:553–559
29.
go back to reference Ivanoff CJ, Sennerby L, Lekholm U (1996) Influence of initial implant mobility on the integration of titanium implants. An experimental study in rabbits. Clin Oral Implants Res 7:120–127CrossRefPubMed Ivanoff CJ, Sennerby L, Lekholm U (1996) Influence of initial implant mobility on the integration of titanium implants. An experimental study in rabbits. Clin Oral Implants Res 7:120–127CrossRefPubMed
30.
go back to reference Meyer U, Vollmer D, Runte C, Bourauel C, Joos U (2001) Bone loading pattern around implants in average and atrophic edentulous maxillae: a finite element analysis. J Craniomaxillofac Surg 29:100–105PubMed Meyer U, Vollmer D, Runte C, Bourauel C, Joos U (2001) Bone loading pattern around implants in average and atrophic edentulous maxillae: a finite element analysis. J Craniomaxillofac Surg 29:100–105PubMed
31.
go back to reference Lindquist LW, Carlsson GE, Glantz PO (1987) Rehabilitation of the edentulous mandible with a tissue integrated fixed prosthesis: a six year longitudinal study. Quintessence Int 18:89–96PubMed Lindquist LW, Carlsson GE, Glantz PO (1987) Rehabilitation of the edentulous mandible with a tissue integrated fixed prosthesis: a six year longitudinal study. Quintessence Int 18:89–96PubMed
32.
go back to reference Hobkirk JA, Psarros KJ (1992) The influence of occlusal surface material on peak masticatory forces using osseointegrated implant-supported prostheses. Int J Oral Maxillofac Implants 7:345–352PubMed Hobkirk JA, Psarros KJ (1992) The influence of occlusal surface material on peak masticatory forces using osseointegrated implant-supported prostheses. Int J Oral Maxillofac Implants 7:345–352PubMed
33.
go back to reference Gracis SE, Nicholls JI, Chalupnik JD, Yuodelis RA (1991) Shock-absorbing behavior of five restorative materials used on implants. Int J Prosthodont 4:282–291PubMed Gracis SE, Nicholls JI, Chalupnik JD, Yuodelis RA (1991) Shock-absorbing behavior of five restorative materials used on implants. Int J Prosthodont 4:282–291PubMed
34.
go back to reference Duyck J, Van Oosterwyck H, Vander Sloten J, De Cooman M, Puers R, Naert I (2000) Influence of prosthesis material on the loading of implants that support a fixed partial prosthesis: in vivo study. Clin Implant Dent Relat Res 2:100–109CrossRefPubMed Duyck J, Van Oosterwyck H, Vander Sloten J, De Cooman M, Puers R, Naert I (2000) Influence of prosthesis material on the loading of implants that support a fixed partial prosthesis: in vivo study. Clin Implant Dent Relat Res 2:100–109CrossRefPubMed
35.
go back to reference Sertgöz A (1997) Finite element analysis study of the effect of superstructure material on stress distribution in an implant supported fixed prosthesis. Int J Prosthodont 10:19–27PubMed Sertgöz A (1997) Finite element analysis study of the effect of superstructure material on stress distribution in an implant supported fixed prosthesis. Int J Prosthodont 10:19–27PubMed
36.
go back to reference Cibirka RM, Razzoog ME, Lang BR, Stohler CS (1992) Determining the force absorption quotient for restorative materials used in implant occlusal surfaces. J Prosthet Dent 67:361–364CrossRefPubMed Cibirka RM, Razzoog ME, Lang BR, Stohler CS (1992) Determining the force absorption quotient for restorative materials used in implant occlusal surfaces. J Prosthet Dent 67:361–364CrossRefPubMed
37.
go back to reference Bassit R, Lindström H, Rangert B (2002) In vivo registration of force development with ceramic and acrylic resin occlusal materials on implant-supported prostheses. Int J Oral Maxillofac Implants 17:17–23PubMed Bassit R, Lindström H, Rangert B (2002) In vivo registration of force development with ceramic and acrylic resin occlusal materials on implant-supported prostheses. Int J Oral Maxillofac Implants 17:17–23PubMed
38.
go back to reference Miyata T, Kobayashi Y, Araki H, Ohto T, Shin K (2002) The influence of controlled occlusal overload on peri-implant tissue. Part 4: a histologic study in monkeys. Int J Oral Maxillofac Implants 17:384–390PubMed Miyata T, Kobayashi Y, Araki H, Ohto T, Shin K (2002) The influence of controlled occlusal overload on peri-implant tissue. Part 4: a histologic study in monkeys. Int J Oral Maxillofac Implants 17:384–390PubMed
39.
go back to reference Isidor F (2006) Influence of forces on peri-implant bone. Clin Oral Implants Res 17(Suppl.2):8–18CrossRefPubMed Isidor F (2006) Influence of forces on peri-implant bone. Clin Oral Implants Res 17(Suppl.2):8–18CrossRefPubMed
Metadata
Title
Peri-implant bone reactions around immediately loaded conical implants with different prosthetic suprastructures: histological and histomorphometrical study on minipigs
Authors
Bartolomeo Assenza
Antonio Scarano
Vittoria Perrotti
Iole Vozza
Alessandro Quaranta
Manlio Quaranta
Adriano Piattelli
Giovanna Iezzi
Publication date
01-06-2010
Publisher
Springer-Verlag
Published in
Clinical Oral Investigations / Issue 3/2010
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-009-0289-x

Other articles of this Issue 3/2010

Clinical Oral Investigations 3/2010 Go to the issue