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Clinical Oral Investigations
Published in: Clinical Oral Investigations 1/2005

01-03-2005 | Original Article

Formation of human cementum following different modalities of regenerative therapy

Authors: A. Sculean, A. Stavropoulos, M. Berakdar, P. Windisch, T. Karring, M. Brecx

Published in: Clinical Oral Investigations | Issue 1/2005

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Abstract

The aim of the present study was to compare newly formed cementum following different types of regenerative therapy in humans. Eighteen patients, each displaying one advanced intrabony defect around teeth scheduled for extraction, were included in this study. The defects were treated with either guided tissue regeneration (GTR), enamel matrix protein derivative (EMD), EMD plus bioactive glass, bovine-derived xenograft (BDX), BDX plus GTR, or BDX plus EMD. After healing, the teeth were removed together with their surrounding soft and hard tissues. Cellular content, presence of artifactual splits between the new cementum and the old one or the dentin surface, and thickness of the new cementum were evaluated. Irrespective of treatment, the new cementum was of a reparative, cellular, extrinsic and intrinsic fiber type. There were no differences in cementum thickness among treatments. These findings indicate that in humans, (a) the new cementum formed after different types of regenerative therapy was, irrespective of the treatment, of a reparative, cellular, extrinsic and intrinsic fiber type, and (b) the regenerative modality does not seem to influence the type of newly formed cementum.
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Metadata
Title
Formation of human cementum following different modalities of regenerative therapy
Authors
A. Sculean
A. Stavropoulos
M. Berakdar
P. Windisch
T. Karring
M. Brecx
Publication date
01-03-2005
Publisher
Springer-Verlag
Published in
Clinical Oral Investigations / Issue 1/2005
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-004-0288-x

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