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Published in: Journal of Bone and Mineral Metabolism 2/2019

01-03-2019 | Original Article

Failure in diagnosis and under-treatment of osteoporosis in elderly patients with fragility fractures

Authors: Sofia Bougioukli, Panagoula Κollia, Theodora Koromila, Sokratis Varitimidis, Michael Hantes, Theofilos Karachalios, Κonstantinos Ν. Malizos, Zoe H. Dailiana

Published in: Journal of Bone and Mineral Metabolism | Issue 2/2019

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Abstract

We evaluated whether osteoporosis is adequately managed and treated in patients suffering from fragility fractures. Factors that influenced osteoporosis diagnosis and treatment rates were also assessed. To this end, patients with the principal diagnosis of low-energy hip, vertebral, or distal radius fractures were recruited for the study. Collected data included risk factors for osteoporosis, history of previous fractures, known history of osteoporosis, and osteoporosis treatment at the time of admission. The patients’ prefracture risk profile was also assessed to determine whether osteoporosis could have been identified prior to the index fracture. We identified 308 patients with fragility fractures, including 214 hip, 41 vertebral, and 53 distal radius fractures. Overall, 238 patients (77.3%) had at least one risk factor for osteoporosis. Eighty-eight patients (28.6%) had sustained ≥ 1 prior fragility fractures in the past. However, only 79 patients (25.6%) were aware that they had osteoporosis and even fewer (66 patients, 21.4%) had been receiving osteoporosis treatment preceding the current admission. Anti-osteoporotic agents were more commonly prescribed in patients 66–75 years old (p = 0.008), with a family history of osteoporosis (p = 0.009) or history of a prior fragility fracture (p = 0.012). The treatment rate was higher in women than men (p = 0.026) and in patients with vertebral or multiple prior fractures compared to patients with prior hip fractures. The current study provides evidence that individuals who experience fragility fractures are not adequately managed for osteoporosis. Only few of the historically known risk factors for osteoporosis were adequately recognized and associated with osteoporosis evaluation and treatment.
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Metadata
Title
Failure in diagnosis and under-treatment of osteoporosis in elderly patients with fragility fractures
Authors
Sofia Bougioukli
Panagoula Κollia
Theodora Koromila
Sokratis Varitimidis
Michael Hantes
Theofilos Karachalios
Κonstantinos Ν. Malizos
Zoe H. Dailiana
Publication date
01-03-2019
Publisher
Springer Japan
Published in
Journal of Bone and Mineral Metabolism / Issue 2/2019
Print ISSN: 0914-8779
Electronic ISSN: 1435-5604
DOI
https://doi.org/10.1007/s00774-018-0923-2

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