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01-04-2020 | Brief Report

Characterization of a G9 group A rotavirus reassortant strain detected in Jinzhou, China, in 2018–2019

Authors: Ying Lu, Hui Li, Weiwei Li, Xiaofang Wang, Xiaoli Tao, Lili Dou, Ying Dong, Nan Wu, Yong Gang Li

Published in: Archives of Virology | Issue 4/2020

Abstract

A novel rotavirus A (RVA) strain (JZ) was detected in RVA-positive stool specimens from three pediatric patients in Jinzhou, Liaoning Province, in 2018–2019. The electrophoresis pattern of the JZ strain showed a long electropherotype. The genomic constellation G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E2-H1 was detected, suggesting that a new inter-genogroup reassortment had occurred. Whole-genome sequencing showed that the JZ isolates were identical to each other. Phylogenetic analysis revealed that VP7 and VP4 clustered in lineages G9-VI and P[8]-3, respectively. JZ strain-specific amino acid substitutions were detected in VP7, VP4 and NSP4. This study provides information on the epidemiology and characteristics of G9 strains circulating in China.

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Title: Characterization of a G9 group A rotavirus reassortant strain detected in Jinzhou, China, in 2018–2019
Authors: Ying Lu
Hui Li
Weiwei Li
Xiaofang Wang
Xiaoli Tao
Lili Dou
Ying Dong
Nan Wu
Yong Gang Li
Publication date: 01-04-2020
Publisher: Springer Vienna
Published in: Archives of Virology / Issue 4/2020
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-020-04563-0

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