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Archives of Virology
Published in: Archives of Virology 10/2019

01-10-2019 | Arteritis | Annotated Sequence Record

Complete genome sequence and analysis of a new lethal arterivirus, Trionyx sinensis hemorrhagic syndrome virus (TSHSV), amplified from an infected Chinese softshell turtle

Authors: Sunjian Lyu, Xuemei Yuan, Haiqi Zhang, Weida Shi, Xiaoying Hang, Li Liu, Zheng Cao, Yinglei Wu

Published in: Archives of Virology | Issue 10/2019

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Abstract

Trionyx sinensis hemorrhagic syndrome virus (TSHSV) is a newly discovered lethal arterivirus that causes serious disease in Trionyx sinensis in China. In this study, the complete genome sequence of TSHSV was determined by RACE cloning, and the functions of the predicted proteins were predicted. The complete genome of TSHSV was found to be 17,875 bp in length, and a 3’-end poly(A) tail was detected. Eight TSHSV hypothetical proteins (TSHSV-HPs) were predicted by gene model identification. TSHSV-HP2, 3 and 4 were associated with replicase activity, since papain-like protease (PLPs), serine-type endopeptidase, P-loop-containing nucleoside triphosphate hydrolase, and EndoU-like endoribonuclease motifs were detected. Phylogenetic analysis showed that TSHSV clusters with an arterivirus from a Chinese broad-headed pond turtle.
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Metadata
Title
Complete genome sequence and analysis of a new lethal arterivirus, Trionyx sinensis hemorrhagic syndrome virus (TSHSV), amplified from an infected Chinese softshell turtle
Authors
Sunjian Lyu
Xuemei Yuan
Haiqi Zhang
Weida Shi
Xiaoying Hang
Li Liu
Zheng Cao
Yinglei Wu
Publication date
01-10-2019
Publisher
Springer Vienna
Keyword
Arteritis
Published in
Archives of Virology / Issue 10/2019
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-019-04324-8

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