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01-11-2017 | Brief Report

Characterization of reassortant H1-subtype avian influenza viruses isolated from poultry in Zhejiang Province in China from 2013 to 2015

Authors: Haibo Wu, Rufeng Lu, Xiuming Peng, Fumin Liu, Linfang Cheng, Nanping Wu

Published in: Archives of Virology | Issue 11/2017

Abstract

From 2013 to 2015, 32 H1-subtype avian influenza viruses (AIVs), H1N2 (n = 12), H1N3 (n = 14), H1N4 (n = 4) and H1N9 (n = 2), were isolated from poultry in Zhejiang Province in eastern China. These strains were characterized by whole-genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that these strains clustered in the AIV Eurasian lineage. These strains were found to be minimally pathogenic in mice and were able to replicate in mice without prior adaptation. Continued surveillance is needed, considering the important role of poultry in AIV reassortment.

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Title: Characterization of reassortant H1-subtype avian influenza viruses isolated from poultry in Zhejiang Province in China from 2013 to 2015
Authors: Haibo Wu
Rufeng Lu
Xiuming Peng
Fumin Liu
Linfang Cheng
Nanping Wu
Publication date: 01-11-2017
Publisher: Springer Vienna
Published in: Archives of Virology / Issue 11/2017
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-017-3487-x

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