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Archives of Virology
Published in: Archives of Virology 2/2017

01-02-2017 | Original Article

Molecular evidence of Orthopoxvirus DNA in capybara (Hydrochoerus hydrochaeris) stool samples

Authors: Lara Ambrosio Leal Dutra, Gabriel Magno de Freitas Almeida, Graziele Pereira Oliveira, Jônatas Santos Abrahão, Erna Geessien Kroon, Giliane de Souza Trindade

Published in: Archives of Virology | Issue 2/2017

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Abstract

Vaccinia virus (VACV) is responsible for outbreaks in Brazil and has immense potential as an emerging virus. VACV can be found naturally circulating in India, Pakistan and South America, where it causes infections characterised by exanthematic lesions in buffaloes, cattle and humans. The transmission cycle of Brazilian VACV has still not been fully characterised; one of the most important gaps in knowledge being the role of wild animals. Capybaras, which are restricted to the Americas, are the world’s largest rodents and have peculiar characteristics that make them possible candidates for being part of a natural VACV reservoir. Here, we developed a method for detecting orthopoxvirus DNA in capybara stool samples, and have described for the first time the detection of orthopoxvirus DNA in capybaras samples from three different regions in Brazil. These findings strongly suggest that capybaras might be involved in the natural transmission cycle of VACV and furthermore represent a public health problem, when associated with Brazilian bovine vaccinia outbreaks. This makes infected animals an important factor to be considered when predicting and managing Brazilian VACV outbreaks.
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Metadata
Title
Molecular evidence of Orthopoxvirus DNA in capybara (Hydrochoerus hydrochaeris) stool samples
Authors
Lara Ambrosio Leal Dutra
Gabriel Magno de Freitas Almeida
Graziele Pereira Oliveira
Jônatas Santos Abrahão
Erna Geessien Kroon
Giliane de Souza Trindade
Publication date
01-02-2017
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 2/2017
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-016-3121-3

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