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Published in: Archives of Virology 11/2016

01-11-2016 | Brief Report

Complete genomic sequence and comparative analysis of four genital and respiratory isolates of bovine herpesvirus subtype 1.2b (BoHV-1.2b), including the prototype virus strain K22

Authors: Jean M. d’Offay, R. Eberle, Robert W. Fulton, Peter D. Kirkland

Published in: Archives of Virology | Issue 11/2016

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Abstract

Bovine herpesvirus subtype 1.2b (BoHV-1.2b) is associated primarily with bovine infectious pustular vulvovaginitis. We report here the complete genomic sequence of four BoHV-1.2b isolates. The DNA sequence identity of the four genomes is 98.9 %. Differences were primarily in regions containing direct repeats, specifically gene UL36 and the terminal repeat regions immediately flanking gene BICP22. BoHV-1.2b and BoHV-1.1 genomes are similar in size (~135 kb), completely orthologous with respect to regional structure and gene location, and have a 97.5 % DNA sequence homology. The most notable difference is the structure of the DNA replication origin of the two viruses.
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Metadata
Title
Complete genomic sequence and comparative analysis of four genital and respiratory isolates of bovine herpesvirus subtype 1.2b (BoHV-1.2b), including the prototype virus strain K22
Authors
Jean M. d’Offay
R. Eberle
Robert W. Fulton
Peter D. Kirkland
Publication date
01-11-2016
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 11/2016
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-016-3026-1

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