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Archives of Virology
Published in: Archives of Virology 7/2016

01-07-2016 | Original Article

Isolation and genetic characterization of novel reassortant H6N6 subtype avian influenza viruses isolated from chickens in eastern China

Authors: Haibo Wu, Rufeng Lu, Xiuming Peng, Xiaorong Peng, Linfang Cheng, Changzhong Jin, Xiangyun Lu, Tiansheng Xie, Hangping Yao, Nanping Wu

Published in: Archives of Virology | Issue 7/2016

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Abstract

H6 subtype avian influenza viruses (AIVs) possess the ability to cross the species barrier to infect mammals and pose a threat to human health. From June 2014 to July 2015, 12 H6N6 AIVs were isolated from chickens in live-poultry markets in Zhejiang Province, Eastern China. Phylogenetic analysis showed that these isolates received their genes from H6 and H9N2 subtype AIVs of poultry in China. These novel reassortant viruses showed moderate pathogenicity in mice and were able to replicate in mice without prior adaptation. Considering that novel reassorted H6N6 viruses were isolated from chickens in this study, it is possible that these chickens play an important role in the generation of novel reassorted H6N6 AIVs, and these results emphasize the need for continued surveillance of the H6N6 AIVs circulating in poultry.
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Metadata
Title
Isolation and genetic characterization of novel reassortant H6N6 subtype avian influenza viruses isolated from chickens in eastern China
Authors
Haibo Wu
Rufeng Lu
Xiuming Peng
Xiaorong Peng
Linfang Cheng
Changzhong Jin
Xiangyun Lu
Tiansheng Xie
Hangping Yao
Nanping Wu
Publication date
01-07-2016
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 7/2016
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-016-2861-4

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