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01-05-2015 | Brief Report

Molecular and serological evidence for Seoul virus in rats (Rattus norvegicus) in Zhangmu, Tibet, China

Authors: Tingsong Hu, Quanshui Fan, Xiaobing Hu, Bo Deng, Gang Chen, Liangqi Gu, Ming Li, Ying Zheng, Guihong Yuan, Wei Qiu, Xiaomei Jiang, Fuqiang Zhang

Published in: Archives of Virology | Issue 5/2015

Abstract

We report the detection of a virus, tentatively identified as Seoul virus (SEOV), from a rat (Rattus norvegicus) collected in the city of Zhangmu, Tibet. SEOV RNA was detected in lung tissue by reverse transcription (RT)-PCR, followed by sequencing. Serum samples collected from Zhangmu were positive for SEOV-specific antibodies (indirect fluorescent antibody test that used SEO antigen). Sequencing and phylogenetic analysis of partial L and S sequences together with serology results suggest that the Zhangmu01 hantavirus is an isolate of SEOV, that hantaviruses circulate in Tibet, and that rats may act as natural reservoirs for the virus.

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Title: Molecular and serological evidence for Seoul virus in rats (Rattus norvegicus) in Zhangmu, Tibet, China
Authors: Tingsong Hu
Quanshui Fan
Xiaobing Hu
Bo Deng
Gang Chen
Liangqi Gu
Ming Li
Ying Zheng
Guihong Yuan
Wei Qiu
Xiaomei Jiang
Fuqiang Zhang
Publication date: 01-05-2015
Publisher: Springer Vienna
Published in: Archives of Virology / Issue 5/2015
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-015-2391-5

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