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Archives of Virology
Published in: Archives of Virology 11/2012

01-11-2012 | Annotated Sequence Record

Tick-borne encephalitis virus in Eastern Siberia: complete genome characteristics

Authors: Nina V. Kulakova, Evgenii I. Andaev, Sergei I. Belikov

Published in: Archives of Virology | Issue 11/2012

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Abstract

Tick-borne encephalitis (TBE) is one of the most important arboviral diseases across Eurasia. TBE virus (TBEV) is transmitted by tick bite and causes a potentially fatal neurological infection in humans. In the Russian Federation, TBE is endemic in most regions, with 3000-5000 cases of the disease annually. To characterise TBEV in Eastern Siberia, the complete genomes of five TBEV isolates from patients with different clinical manifestations were sequenced. The results show that the Siberian and Far Eastern subtypes of TBEV cause the disease in people in Eastern Siberia. Complete genome analysis revealed an unexpectedly high genetic variability within the Siberian subtype.
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Metadata
Title
Tick-borne encephalitis virus in Eastern Siberia: complete genome characteristics
Authors
Nina V. Kulakova
Evgenii I. Andaev
Sergei I. Belikov
Publication date
01-11-2012
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 11/2012
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-012-1412-x

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