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Archives of Virology
Published in: Archives of Virology 12/2012

01-12-2012 | Brief Report

Genomic and serological detection of bat coronavirus from bats in the Philippines

Authors: Shumpei Tsuda, Shumpei Watanabe, Joseph S. Masangkay, Tetsuya Mizutani, Phillip Alviola, Naoya Ueda, Koichiro Iha, Satoshi Taniguchi, Hikaru Fujii, Kentaro Kato, Taisuke Horimoto, Shigeru Kyuwa, Yasuhiro Yoshikawa, Hiroomi Akashi

Published in: Archives of Virology | Issue 12/2012

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Abstract

Bat coronavirus (BtCoV) is assumed to be a progenitor of severe acute respiratory syndrome (SARS)-related coronaviruses. To explore the distribution of BtCoVs in the Philippines, we collected 179 bats and detected viral RNA from intestinal or fecal samples by RT-PCR. The overall prevalence of BtCoVs among bats was 29.6 %. Phylogenetic analysis of the partial RNA-dependent RNA polymerase gene suggested that one of the detected BtCoVs was a novel alphacoronavirus, while the others belonged to the genus Betacoronavirus. Western blotting revealed that 66.5 % of bat sera had antibodies to BtCoV. These surveys suggested the endemic presence of BtCoVs in the Philippines.
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Metadata
Title
Genomic and serological detection of bat coronavirus from bats in the Philippines
Authors
Shumpei Tsuda
Shumpei Watanabe
Joseph S. Masangkay
Tetsuya Mizutani
Phillip Alviola
Naoya Ueda
Koichiro Iha
Satoshi Taniguchi
Hikaru Fujii
Kentaro Kato
Taisuke Horimoto
Shigeru Kyuwa
Yasuhiro Yoshikawa
Hiroomi Akashi
Publication date
01-12-2012
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 12/2012
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-012-1410-z

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