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01-04-2010 | Brief Report

Molecular detection and genetic diversity of norovirus genogroup IV: a yearlong monitoring of sewage throughout Italy

Authors: Giuseppina La Rosa, Marcello Iaconelli, Manoochehr Pourshaban, Marta Fratini, Michele Muscillo

Published in: Archives of Virology | Issue 4/2010

Abstract

Noroviruses cause acute viral gastroenteritis worldwide. They are classified in five genogroups, of which GI, GII, and GIV infect humans. Little information is available on the prevalence and clinical effects of GIV noroviruses. We conducted a large-scale molecular-epidemiological investigation, a yearlong monitoring of 11 wastewater treatment plants throughout Italy, with the aim of studying the circulation of GIV NoV, as well as its genetic diversity. Eight percent of samples tested positive, and sequence analysis showed a considerable degree of genetic variability. These results imply the need for further studies to elucidate the role of this virus as a gastroenteritis-causing pathogen.

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Title: Molecular detection and genetic diversity of norovirus genogroup IV: a yearlong monitoring of sewage throughout Italy
Authors: Giuseppina La Rosa
Marcello Iaconelli
Manoochehr Pourshaban
Marta Fratini
Michele Muscillo
Publication date: 01-04-2010
Publisher: Springer Vienna
Published in: Archives of Virology / Issue 4/2010
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-010-0619-y

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