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28-02-2024 | Headache | Neurology and Preclinical Neurological Studies - Original Article

Headache patterns in patent foramen ovale patients: beyond migraine with aura

Authors: Raluca Ștefania Badea, N. Grecu, A. C. Ribigan, F. Antochi, C. Tiu, B. O. Popescu

Published in: Journal of Neural Transmission

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Abstract

Patent foramen ovale (PFO) is a common cardiac anomaly linked with cryptogenic strokes and migraine, particularly migraine with aura. This study aims to explore the spectrum of headache disorders in PFO patients, focusing on identifying patterns beyond the well-established migraine-PFO connection. A retrospective observational study was conducted on patients diagnosed with PFO. Headache types were classified using the International Classification of Headache Disorders, 3rd edition. The study analyzed headache prevalence and patterns in PFO patients, comparing those with and without a history of stroke. Of 177 participants, 63 (35.59%) reported headaches. Tension-type headache was the most common (15.25%), followed by migraine without aura (11.30%) and migraine with aura (8.47%). Notably, migraine without aura was more prevalent than migraine with aura, contrasting previous assumptions. No significant differences were found in headache types based on stroke history. The study reveals a diverse spectrum of headache types in PFO patients, with migraine without aura being more common than migraine with aura. These findings suggest a need for broader diagnostic perspective and individualized treatment approaches in PFO patients with headaches.
Literature
go back to reference Faggiano P, Frattini S, Piovesana P, Lorusso R, Chiari E, Scolari F, Padovani A, Cas LD (2012) Low cerebrovascular event rate in subjects with patent foramen ovale and different clinical presentations: results from a prospective non randomized study on a population including patients with and without patent foramen ovale closure. Int J Cardiol 156(1):47–52. https://doi.org/10.1016/j.ijcard.2010.10.032CrossRefPubMed Faggiano P, Frattini S, Piovesana P, Lorusso R, Chiari E, Scolari F, Padovani A, Cas LD (2012) Low cerebrovascular event rate in subjects with patent foramen ovale and different clinical presentations: results from a prospective non randomized study on a population including patients with and without patent foramen ovale closure. Int J Cardiol 156(1):47–52. https://​doi.​org/​10.​1016/​j.​ijcard.​2010.​10.​032CrossRefPubMed
Metadata
Title
Headache patterns in patent foramen ovale patients: beyond migraine with aura
Authors
Raluca Ștefania Badea
N. Grecu
A. C. Ribigan
F. Antochi
C. Tiu
B. O. Popescu
Publication date
28-02-2024
Publisher
Springer Vienna
Published in
Journal of Neural Transmission
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI
https://doi.org/10.1007/s00702-024-02760-8