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01-04-2017 | Neurology and Preclinical Neurological Studies - Short communication

Vasomotor regulation in patients with multiple system atrophy

Authors: Kazumasa Shindo, Mai Tsuchiya, Yuta Ichinose, Kishin Koh, Takanori Hata, Nobuo Yamashiro, Fumikazu Kobayashi, Takamura Nagasaka, Yoshihisa Takiyama

Published in: Journal of Neural Transmission | Issue 4/2017

Abstract

To investigate the vasomotor regulation in multiple system atrophy (MSA), we simultaneously recorded muscle sympathetic nerve activity (MSNA), heart rate, and blood pressure in 14 MSA patients without syncope and 18 healthy subjects. Resting MSNA bursts were significantly less frequent in MSA patients than healthy subjects (p < 0.001), while the increase of MSNA bursts with head-up tilt was significantly greater in MSA patients (p < 0.01). In patients with MSA, orthostatic hypotension may be prevented by an augmented MSNA response.

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Title: Vasomotor regulation in patients with multiple system atrophy
Authors: Kazumasa Shindo
Mai Tsuchiya
Yuta Ichinose
Kishin Koh
Takanori Hata
Nobuo Yamashiro
Fumikazu Kobayashi
Takamura Nagasaka
Yoshihisa Takiyama
Publication date: 01-04-2017
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 4/2017
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-016-1644-0

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Vasomotor regulation in patients with multiple system atrophy

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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