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Published in: Journal of Neural Transmission 11/2012

01-11-2012 | Neurology and Preclinical Neurological Studies - CONy Pro/Con debate

Essential tremor is a neurodegenerative disease

Author: Ubaldo Bonuccelli

Published in: Journal of Neural Transmission | Issue 11/2012

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Abstract

There are many lines of evidence supporting the idea that essential tremor is more than simply a monosymptomatic disorder and that all the clinical manifestations of this frequent disorder are sustained by a neurodegenerative process. The most important lines of evidence in favor of a neurodegenerative nature of essential tremor are: the anatomic and neuroimaging data demonstrating a pathologic process involving the cerebellum and/or brainstem; the progression of symptom severity with disease duration; and the lack of spontaneous remission of this condition. All of this evidence is supported by recent studies that are summarized in this review.
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Metadata
Title
Essential tremor is a neurodegenerative disease
Author
Ubaldo Bonuccelli
Publication date
01-11-2012
Publisher
Springer Vienna
Published in
Journal of Neural Transmission / Issue 11/2012
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI
https://doi.org/10.1007/s00702-012-0878-8

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