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Published in: Acta Neurochirurgica 9/2019

Open Access 01-09-2019 | Myelography | Original Article - Spine - Other

Management of perineural (Tarlov) cysts: a population-based cohort study and algorithm for the selection of surgical candidates

Authors: Alexander Fletcher-Sandersjöö, Sadia Mirza, Gustav Burström, Kyrre Pedersen, Åsa Kuntze Söderqvist, Per Grane, Michael Fagerlund, Erik Edström, Adrian Elmi-Terander

Published in: Acta Neurochirurgica | Issue 9/2019

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Abstract

Objective

Perineural cysts, also known as Tarlov cysts, are cerebrospinal fluid-filled growths that develop at the intersection of a dorsal root ganglion and posterior nerve root. They are typically an asymptomatic and incidental finding during routine spine imaging. For symptomatic perineural cysts, there is little evidence on which treatment is most effective or when it is indicated. The aim of this study was to review our experience from a population-based cohort of patients with symptomatic perineural cysts and to propose an algorithm that could be used in the selection of surgical candidates.

Methods

A retrospective review was conducted of all adult (≥ 15 years) patients with symptomatic perineural cysts who were referred to Karolinska University Hospital between 2002 and 2018.

Results

Thirty-nine patients were included. The most common symptom was sciatica (n = 22). Cyst aspiration was performed in 28 patients, 24 of whom showed clinical improvement and were offered surgery. Microsurgical cyst fenestration was performed in 17 patients, 16 of whom showed clinical improvement at long-term follow-up. There were no surgical complications. Ten of the patients who were offered surgery chose to be treated conservatively instead, four of whom showed progression of symptoms at long-term follow-up.

Conclusions

Microsurgical cyst fenestration seems to be a safe and effective option for symptomatic relief in patients with perineural cysts. Based on the results from our series and those of others, we propose an algorithm for the selection of surgical candidates.
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Metadata
Title
Management of perineural (Tarlov) cysts: a population-based cohort study and algorithm for the selection of surgical candidates
Authors
Alexander Fletcher-Sandersjöö
Sadia Mirza
Gustav Burström
Kyrre Pedersen
Åsa Kuntze Söderqvist
Per Grane
Michael Fagerlund
Erik Edström
Adrian Elmi-Terander
Publication date
01-09-2019
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 9/2019
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-019-04000-5

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