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Published in: Acta Neurochirurgica 6/2019

01-06-2019 | Stroke | Original Article - Vascular Neurosurgery - Ischemia

Frontline contact aspiration thrombectomy using SOFIA catheter for acute ischemic stroke: period-to-period comparison with Penumbra catheter

Authors: Yong-Won Kim, Yang-Ha Hwang, Yong-Sun Kim, Dong-Hun Kang

Published in: Acta Neurochirurgica | Issue 6/2019

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Abstract

Background

Recent aspiration thrombectomy devices tend to have a more flexible distal tip and larger bore for easy target access and effective reperfusion. Here, this study primarily focused on the efficacy and safety of the SOFIA catheters when it was used as a frontline contact aspiration thrombectomy (CAT) tool for acute intracranial large vessel occlusion in comparison with the data from a period when the Penumbra catheter was used.

Methods

The subjects comprised 189 patients who underwent CAT (90 with Penumbra Max family and 99 with SOFIA/SOFIA plus). Patients’ data were retrospectively analyzed to evaluate overall clinical and angiographic outcomes and compared between the devices.

Results

Baseline characteristics were similar between groups. But, intravenous alteplase was more frequently administered in the Penumbra group (43.3% vs. 29.3%, p = 0.045), while incidence of ICA occlusion was higher in SOFIA group (18.9% vs. 38.4%, p = 0.013). The modified thrombolysis in cerebral infarction 2b-3 of reperfusion was 94.4% for the Penumbra group and 92.9% for the SOFIA group (p = 0.656). The first-pass effect was more frequently achieved in the SOFIA group (20.0% vs. 39.4%, p = 0.004) and endovascular procedure time was significantly shorter (55.5 min vs. 36 min, p < 0.001). However, clinical outcomes did not differ significantly regarding mortality (11.1% vs. 6.1%, p = 0.213), hemorrhagic complications, and mRS 0–2 at 3 months (63.3% vs. 58.6%; p = 0.504).

Conclusion

CAT using SOFIA may be safe and comparable to thrombectomy using the Penumbra reperfusion catheter. And, the SOFIA catheter could be advantageous for rapid reperfusion and first-pass effect without any significant complications.
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Metadata
Title
Frontline contact aspiration thrombectomy using SOFIA catheter for acute ischemic stroke: period-to-period comparison with Penumbra catheter
Authors
Yong-Won Kim
Yang-Ha Hwang
Yong-Sun Kim
Dong-Hun Kang
Publication date
01-06-2019
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 6/2019
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-019-03914-4

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