Skip to main content
Top
Published in: Surgery Today 3/2020

01-03-2020 | Rectal Cancer | Original Article

Short- and long-term outcomes of robotic surgery for rectal cancer: a single-center retrospective cohort study

Authors: Hidetoshi Katsuno, Tsunekazu Hanai, Koji Masumori, Yoshikazu Koide, Hiroshi Matsuoka, Yosuke Tajima, Tomoyoshi Endo, Masahiro Mizuno, Yongchol Chong, Kotaro Maeda, Ichiro Uyama

Published in: Surgery Today | Issue 3/2020

Login to get access

Abstract

Purpose

This study aimed to clarify the short- and long-term outcomes of robotic surgery with or without lateral lymph node dissection (LLND) for rectal cancer at Fujita Health University Hospital, Aichi, Japan, during a self-pay period.

Methods

We retrospectively evaluated 115 consecutive patients who underwent robotic surgery for rectal cancer between September 2009 and March 2018, with a median follow-up period of 48 months. Total mesorectal excision was completed by two certified surgeons using a da Vinci S, Si, or Xi Surgical System with an entirely robotic single-docking technique. The surgical and pathological outcomes, morbidity, and oncological results were examined.

Results

Lateral lymph node dissection was performed in 26 patients (22.6%). Neither conversion to open surgery nor perioperative blood transfusion occurred. Ten patients (8.7%) experienced Clavien–Dindo grade III postoperative complications. Pathologically, both the distal and radial margins were negative in all cases. The 5-year relapse-free survival rates for stages I, II, III, and IV were 93.5%, 100%, 83.8%, and not reached, respectively.

Conclusions

Even in the period before coverage by the health insurance system, robotic surgery for rectal cancer performed by experienced surgeons was safe and technically feasible, with favorable perioperative results and long-term oncological outcomes, including rates of the relapse-free survival.
Literature
1.
go back to reference Bandoh T, Shiraishi N, Yamashita Y, Terachi T, Hashizume M, Akira S, et al. Endoscopic surgery in Japan: the 12th national survey (2012–2013) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2017;10:345–53.CrossRef Bandoh T, Shiraishi N, Yamashita Y, Terachi T, Hashizume M, Akira S, et al. Endoscopic surgery in Japan: the 12th national survey (2012–2013) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2017;10:345–53.CrossRef
2.
go back to reference Shiroshita H, Inomata M, Bandoh T, Uchida H, Akira S, Hashizume M, et al. Endoscopic surgery in Japan: the 13th national survey (2014–2015) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2019;12:7–18.CrossRef Shiroshita H, Inomata M, Bandoh T, Uchida H, Akira S, Hashizume M, et al. Endoscopic surgery in Japan: the 13th national survey (2014–2015) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2019;12:7–18.CrossRef
3.
go back to reference Watanabe T, Muro K, Ajioka Y, Hashiguchi Y, Ito Y, Saito Y, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer. Int J Clin Oncol. 2018;23:1–34.CrossRef Watanabe T, Muro K, Ajioka Y, Hashiguchi Y, Ito Y, Saito Y, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer. Int J Clin Oncol. 2018;23:1–34.CrossRef
4.
go back to reference Fleshman J, Branda ME, Sargent DJ, Boller AM, George VV, Abbas MA, et al. Disease-free survival and local recurrence for laparoscopic resection compared with open resection of stage II to III rectal cancer: follow-up results of the ACOSOG Z6051 randomized controlled trial. Ann Surg. 2019;269:589–95.CrossRef Fleshman J, Branda ME, Sargent DJ, Boller AM, George VV, Abbas MA, et al. Disease-free survival and local recurrence for laparoscopic resection compared with open resection of stage II to III rectal cancer: follow-up results of the ACOSOG Z6051 randomized controlled trial. Ann Surg. 2019;269:589–95.CrossRef
5.
go back to reference Stevenson AR, Solomon MJ, Lumley JW, Hewett P, Clouston AD, Gebski VJ, et al. Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial. JAMA. 2015;314:1356–63.CrossRef Stevenson AR, Solomon MJ, Lumley JW, Hewett P, Clouston AD, Gebski VJ, et al. Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial. JAMA. 2015;314:1356–63.CrossRef
6.
go back to reference Jayne D, Pigazzi A, Marshall H, Croft J, Corrigan N, Copeland J, et al. Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial. JAMA. 2017;318:1569–80.CrossRef Jayne D, Pigazzi A, Marshall H, Croft J, Corrigan N, Copeland J, et al. Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial. JAMA. 2017;318:1569–80.CrossRef
9.
go back to reference Phan K, Kahlaee HR, Kim SH, Toh JWT. Laparoscopic vs. robotic rectal cancer surgery and the effect on conversion rates: a meta-analysis of randomized controlled trials and propensity-score-matched studies. Tech Coloproctol. 2019;23:221–30.CrossRef Phan K, Kahlaee HR, Kim SH, Toh JWT. Laparoscopic vs. robotic rectal cancer surgery and the effect on conversion rates: a meta-analysis of randomized controlled trials and propensity-score-matched studies. Tech Coloproctol. 2019;23:221–30.CrossRef
10.
go back to reference Katsuno H, Maeda K, Hanai T, Masumori K, Matsuoka H, Uyama I, et al. A novel approach of robot surgery for colorectal cancer. Jpn J Gastroenterol Surg. 2010;43:1002–6.CrossRef Katsuno H, Maeda K, Hanai T, Masumori K, Matsuoka H, Uyama I, et al. A novel approach of robot surgery for colorectal cancer. Jpn J Gastroenterol Surg. 2010;43:1002–6.CrossRef
11.
go back to reference Kanehara & Co., Ltd. Japanese society for cancer of the colon and rectum. Japanese classification of colorectal carcinoma. Tokyo: Kanehara & Co., Ltd; 2009 (2nd English ed). Kanehara & Co., Ltd. Japanese society for cancer of the colon and rectum. Japanese classification of colorectal carcinoma. Tokyo: Kanehara & Co., Ltd; 2009 (2nd English ed).
12.
go back to reference Brierley J, Gospodarowicz MK, Wittekind C. TNM classification of the malignant tumours. 8th ed. Chichester: Wiley; 2017. Brierley J, Gospodarowicz MK, Wittekind C. TNM classification of the malignant tumours. 8th ed. Chichester: Wiley; 2017.
13.
go back to reference Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.CrossRef Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.CrossRef
14.
go back to reference Feroci F, Vannucchi A, Bianchi PP, Cantafio S, Garzi A, Formisano G, et al. Total mesorectal excision for mid and low rectal cancer: laparoscopic vs robotic surgery. World J Gastroenterol. 2016;22:3602–10.CrossRef Feroci F, Vannucchi A, Bianchi PP, Cantafio S, Garzi A, Formisano G, et al. Total mesorectal excision for mid and low rectal cancer: laparoscopic vs robotic surgery. World J Gastroenterol. 2016;22:3602–10.CrossRef
15.
go back to reference Aselmann H, Kersebaum JN, Bernsmeier A, Beckmann JH, Moller T, Egberts JH, et al. Robotic-assisted total mesorectal excision (TME) for rectal cancer results in a significantly higher quality of TME specimen compared to the laparoscopic approach-report of a single-center experience. Int J Colorectal Dis. 2018;33:1575–81.CrossRef Aselmann H, Kersebaum JN, Bernsmeier A, Beckmann JH, Moller T, Egberts JH, et al. Robotic-assisted total mesorectal excision (TME) for rectal cancer results in a significantly higher quality of TME specimen compared to the laparoscopic approach-report of a single-center experience. Int J Colorectal Dis. 2018;33:1575–81.CrossRef
16.
go back to reference Bokhari MB, Patel CB, Ramos-Valadez DI, Ragupathi M, Haas EM. Learning curve for robotic-assisted laparoscopic colorectal surgery. Surg Endosc. 2011;25:855–60.CrossRef Bokhari MB, Patel CB, Ramos-Valadez DI, Ragupathi M, Haas EM. Learning curve for robotic-assisted laparoscopic colorectal surgery. Surg Endosc. 2011;25:855–60.CrossRef
17.
go back to reference Jiménez-Rodríiguez RM, Díaz-Pavón JM, de la Portilla de Juan F, Prendes-Sillero E, Dussort HC, Padillo J. Learning curve for robotic-assisted laparoscopic rectal cancer surgery. Int J Colorectal Dis. 2012;28:815–21.CrossRef Jiménez-Rodríiguez RM, Díaz-Pavón JM, de la Portilla de Juan F, Prendes-Sillero E, Dussort HC, Padillo J. Learning curve for robotic-assisted laparoscopic rectal cancer surgery. Int J Colorectal Dis. 2012;28:815–21.CrossRef
18.
go back to reference Morelli L, Di Franco G, Guadagni S, Rossi L, Palmeri M, Furbetta N, et al. Robot-assisted total mesorectal excision for rectal cancer: case-matched comparison of short-term surgical and functional outcomes between the da Vinci Xi and Si. Surg Endosc. 2018;32:589–600.CrossRef Morelli L, Di Franco G, Guadagni S, Rossi L, Palmeri M, Furbetta N, et al. Robot-assisted total mesorectal excision for rectal cancer: case-matched comparison of short-term surgical and functional outcomes between the da Vinci Xi and Si. Surg Endosc. 2018;32:589–600.CrossRef
19.
go back to reference Memon S, Heriot AG, Murphy DG, Bressel M, Lynch AC. Robotic versus laparoscopic proctectomy for rectal cancer: a meta-analysis. Ann Surg Oncol. 2012;19:2095–101.CrossRef Memon S, Heriot AG, Murphy DG, Bressel M, Lynch AC. Robotic versus laparoscopic proctectomy for rectal cancer: a meta-analysis. Ann Surg Oncol. 2012;19:2095–101.CrossRef
20.
go back to reference Huang YJ, Kang YN, Huang YM, Wu AT, Wang W, Wei PL. Effects of laparoscopic vs robotic-assisted mesorectal excision for rectal cancer: an update systematic review and meta-analysis of randomized controlled trials. Asian J Surg. 2019;42:657–66.CrossRef Huang YJ, Kang YN, Huang YM, Wu AT, Wang W, Wei PL. Effects of laparoscopic vs robotic-assisted mesorectal excision for rectal cancer: an update systematic review and meta-analysis of randomized controlled trials. Asian J Surg. 2019;42:657–66.CrossRef
21.
go back to reference Mori T, Kimura T, Kitajima M. Skill accreditation system for laparoscopic gastroenterologic surgeons in Japan. Minim Invasive Ther Allied Technol. 2010;19:18–23.CrossRef Mori T, Kimura T, Kitajima M. Skill accreditation system for laparoscopic gastroenterologic surgeons in Japan. Minim Invasive Ther Allied Technol. 2010;19:18–23.CrossRef
22.
go back to reference Crolla R, Mulder PG, van der Schelling GP. Does robotic rectal cancer surgery improve the results of experienced laparoscopic surgeons? An observational single institution study comparing 168 robotic assisted with 184 laparoscopic rectal resections. Surg Endosc. 2018;32:4562–70.CrossRef Crolla R, Mulder PG, van der Schelling GP. Does robotic rectal cancer surgery improve the results of experienced laparoscopic surgeons? An observational single institution study comparing 168 robotic assisted with 184 laparoscopic rectal resections. Surg Endosc. 2018;32:4562–70.CrossRef
23.
go back to reference Tang B, Zhang C, Li C, Chen J, Luo H, Zeng D, et al. Robotic total mesorectal excision for rectal cancer: a series of 392 cases and mid-term outcomes from a single center in China. J Gastrointest Surg. 2017;21:569–76.CrossRef Tang B, Zhang C, Li C, Chen J, Luo H, Zeng D, et al. Robotic total mesorectal excision for rectal cancer: a series of 392 cases and mid-term outcomes from a single center in China. J Gastrointest Surg. 2017;21:569–76.CrossRef
24.
go back to reference Law WL, Foo DCC. Comparison of short-term and oncologic outcomes of robotic and laparoscopic resection for mid- and distal rectal cancer. Surg Endosc. 2017;31:2798–807.CrossRef Law WL, Foo DCC. Comparison of short-term and oncologic outcomes of robotic and laparoscopic resection for mid- and distal rectal cancer. Surg Endosc. 2017;31:2798–807.CrossRef
25.
go back to reference Hara M, Sng K, Yoo BE, Shin JW, Lee DW, Kim SH. Robotic-assisted surgery for rectal adenocarcinoma: short-term and midterm outcomes from 200 consecutive cases at a single institution. Dis Colon Rectum. 2014;57:570–7.CrossRef Hara M, Sng K, Yoo BE, Shin JW, Lee DW, Kim SH. Robotic-assisted surgery for rectal adenocarcinoma: short-term and midterm outcomes from 200 consecutive cases at a single institution. Dis Colon Rectum. 2014;57:570–7.CrossRef
26.
go back to reference Pridgeon S, Bishop CV, Adshead J. Lower limb compartment syndrome as a complication of robot-assisted radical prostatectomy: the UK experience. BJU Int. 2013;112:485–8.CrossRef Pridgeon S, Bishop CV, Adshead J. Lower limb compartment syndrome as a complication of robot-assisted radical prostatectomy: the UK experience. BJU Int. 2013;112:485–8.CrossRef
27.
go back to reference Bonjer HJ, Deijen CL, Abis GA, Cuesta MA, van der Pas MH, de Lange-de Klerk ES, et al. A randomized trial of laparoscopic versus open surgery for rectal cancer. N Engl J Med. 2015;372:1324–32.CrossRef Bonjer HJ, Deijen CL, Abis GA, Cuesta MA, van der Pas MH, de Lange-de Klerk ES, et al. A randomized trial of laparoscopic versus open surgery for rectal cancer. N Engl J Med. 2015;372:1324–32.CrossRef
28.
go back to reference Patriti A, Ceccarelli G, Bartoli A, Spaziani A, Lapalorcia LM, Casciola L. Laparoscopic and robot-assisted one-stage resection of colorectal cancer with synchronous liver metastases: a pilot study. J Hepatobiliary Pancreat Surg. 2009;16:450–7.CrossRef Patriti A, Ceccarelli G, Bartoli A, Spaziani A, Lapalorcia LM, Casciola L. Laparoscopic and robot-assisted one-stage resection of colorectal cancer with synchronous liver metastases: a pilot study. J Hepatobiliary Pancreat Surg. 2009;16:450–7.CrossRef
29.
go back to reference Sugihara K, Kobayashi H, Kato T, Mori T, Mochizuki H, Kameoka S, et al. Indication and benefit of pelvic sidewall dissection for rectal cancer. Dis Colon Rectum. 2006;49:1663–72.CrossRef Sugihara K, Kobayashi H, Kato T, Mori T, Mochizuki H, Kameoka S, et al. Indication and benefit of pelvic sidewall dissection for rectal cancer. Dis Colon Rectum. 2006;49:1663–72.CrossRef
30.
go back to reference Sato H, Maeda K, Maruta M. Prognostic significance of lateral lymph node dissection in node positive low rectal carcinoma. Int J Colorectal Dis. 2011;26:881–9.CrossRef Sato H, Maeda K, Maruta M. Prognostic significance of lateral lymph node dissection in node positive low rectal carcinoma. Int J Colorectal Dis. 2011;26:881–9.CrossRef
31.
go back to reference Heald RJ, Husband EM, Ryall RD. The mesorectum in rectal cancer surgery–the clue to pelvic recurrence? Br J Surg. 1982;69:613–6.CrossRef Heald RJ, Husband EM, Ryall RD. The mesorectum in rectal cancer surgery–the clue to pelvic recurrence? Br J Surg. 1982;69:613–6.CrossRef
32.
go back to reference Maeda K, Hanai T, Sato H, Masumori K, Koide Y, Matsuoka H, et al. Intraluminal exfoliated cancer cells and effectiveness of bowel ligatures during sigmoidectomy for sigmoid colon cancer. Surg Today. 2014;44:297–301.CrossRef Maeda K, Hanai T, Sato H, Masumori K, Koide Y, Matsuoka H, et al. Intraluminal exfoliated cancer cells and effectiveness of bowel ligatures during sigmoidectomy for sigmoid colon cancer. Surg Today. 2014;44:297–301.CrossRef
33.
go back to reference Hu Y, Feit N, Huang Y, Xu W, Zheng S, Li X. Gastrointestinal metastasis of primary lung cancer: an analysis of 366 cases. Oncol Lett. 2018;15:9766–76.PubMedPubMedCentral Hu Y, Feit N, Huang Y, Xu W, Zheng S, Li X. Gastrointestinal metastasis of primary lung cancer: an analysis of 366 cases. Oncol Lett. 2018;15:9766–76.PubMedPubMedCentral
34.
go back to reference Kim J, Baek SJ, Kang DW, Roh YE, Lee JW, Kwak HD, et al. Robotic resection is a good prognostic factor in rectal cancer compared with laparoscopic resection: long-term survival analysis using propensity score matching. Dis Colon Rectum. 2017;60:266–73.CrossRef Kim J, Baek SJ, Kang DW, Roh YE, Lee JW, Kwak HD, et al. Robotic resection is a good prognostic factor in rectal cancer compared with laparoscopic resection: long-term survival analysis using propensity score matching. Dis Colon Rectum. 2017;60:266–73.CrossRef
Metadata
Title
Short- and long-term outcomes of robotic surgery for rectal cancer: a single-center retrospective cohort study
Authors
Hidetoshi Katsuno
Tsunekazu Hanai
Koji Masumori
Yoshikazu Koide
Hiroshi Matsuoka
Yosuke Tajima
Tomoyoshi Endo
Masahiro Mizuno
Yongchol Chong
Kotaro Maeda
Ichiro Uyama
Publication date
01-03-2020
Publisher
Springer Singapore
Published in
Surgery Today / Issue 3/2020
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-019-01874-x

Other articles of this Issue 3/2020

Surgery Today 3/2020 Go to the issue