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Published in: Surgery Today 10/2019

01-10-2019 | Computed Tomography | Original Article

A comparison between 2- and 3-dimensional approaches to solid component measurement as radiological criteria for sublobar resection in lung adenocarcinoma ≤ 2 cm in size

Authors: Yukihiro Yoshida, Toshiki Manaka, Jun-ichi Nitadori, Aya Shinozaki-Ushiku, Takehito Doke, Toki Saito, Jiro Sato, Tempei Miyaji, Takuhiro Yamaguchi, Hiroshi Oyama, Masashi Fukayama, Yoshikazu Nakajima, Jun Nakajima

Published in: Surgery Today | Issue 10/2019

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Abstract

Purpose

We compared three-dimensional (3D) and two-dimensional (2D) measurements of the solid component to determine radiological criteria for sublobar resection of lung adenocarcinoma ≤ 2 cm in size.

Methods

We included 233 surgical cases. The maximum size of the solid component for 3D measurement was calculated by delineating the solid component on successive axial images and reconstructing the 3D surface model.

Results

The predictive performance for adenocarcinoma in situ (n = 43) and minimally invasive adenocarcinoma (n = 77) were equivalent to areas under the curve of 0.871 and 0.857 for 2D and 3D measurements (p = 0.229), respectively. A solid component of 5 mm had a prognostic impact on both measurements ( ≤ 5 mm versus > 5 mm; p = 0.003 for 2D and p = 0.002 for 3D, log-rank test). Survival rates at 5 years were 94.7–96.9% following lobectomy and sublobar resection among patients with a solid component ≤ 5 mm in size. Sublobar resection resulted in worse survival rates, with declines at 5 years of 15.8% on 2D and 11.5% on 3D measurements, than lobectomy in patients with a solid component > 5 mm in size.

Conclusions

A solid component ≤ 5 mm in size is an appropriate criterion for sublobar resection for both measurements. In addition, 2D measurement is justified because of its simple implementation.
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Metadata
Title
A comparison between 2- and 3-dimensional approaches to solid component measurement as radiological criteria for sublobar resection in lung adenocarcinoma ≤ 2 cm in size
Authors
Yukihiro Yoshida
Toshiki Manaka
Jun-ichi Nitadori
Aya Shinozaki-Ushiku
Takehito Doke
Toki Saito
Jiro Sato
Tempei Miyaji
Takuhiro Yamaguchi
Hiroshi Oyama
Masashi Fukayama
Yoshikazu Nakajima
Jun Nakajima
Publication date
01-10-2019
Publisher
Springer Singapore
Published in
Surgery Today / Issue 10/2019
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-019-01806-9

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