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Surgery Today
Published in: Surgery Today 5/2018

01-05-2018 | Original Article

Risk and incidence of perioperative deep vein thrombosis in patients undergoing gastric cancer surgery

Authors: Tomohiro Osaki, Hiroaki Saito, Yoji Fukumoto, Yusuke Kono, Yuki Murakami, Yuji Shishido, Hirohiko Kuroda, Tomoyuki Matsunaga, Kengo Sato, Yasuaki Hirooka, Yoshiyuki Fujiwara

Published in: Surgery Today | Issue 5/2018

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Abstract

Background and purpose

Venous thromboembolism (VTE) is a potentially fatal perioperative complication. Understanding the risk factors for deep vein thrombosis (DVT) and initiating appropriate prophylaxis is pivotal for reducing the risk of VTE. The purpose of this study was to clarify the perioperative risk factors for DVT in patients undergoing surgery for gastric cancer.

Methods

We reviewed the findings of lower limb ultrasonography performed in 160 patients who underwent gastrectomy for gastric cancer.

Results

The preoperative and postoperative incidence of DVT was 4.4% (7/160) and 7.2% (11/153), respectively. All postoperative DVTs were of the distal type, whereas preoperative DVTs were of the proximal (n = 3) and distal type (n = 4). None of the patients suffered symptomatic VTE. Multivariate analysis indicated that depth of invasion and D-dimer concentration were independent risk factors for preoperative DVT and that gender and performance status were risk factors for postoperative DVT. Receiver operating characteristic analysis revealed that the optimal cut-off D-dimer concentration was 1.4 μg/mL.

Conclusions

The incidence of perioperative DVT was low for patients undergoing gastric cancer surgery. Therefore, the risk-stratified application of perioperative pharmacologic thromboprophylaxis is thought to be more appropriate than routine pharmacologic thromboprophylaxis for Japanese patients undergoing surgery for gastric cancer.
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Metadata
Title
Risk and incidence of perioperative deep vein thrombosis in patients undergoing gastric cancer surgery
Authors
Tomohiro Osaki
Hiroaki Saito
Yoji Fukumoto
Yusuke Kono
Yuki Murakami
Yuji Shishido
Hirohiko Kuroda
Tomoyuki Matsunaga
Kengo Sato
Yasuaki Hirooka
Yoshiyuki Fujiwara
Publication date
01-05-2018
Publisher
Springer Singapore
Published in
Surgery Today / Issue 5/2018
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-017-1617-4

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