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Published in: Surgery Today 2/2017

01-02-2017 | Original Article

Quantitative assessment technique of HyperEye medical system angiography for coronary artery bypass grafting

Authors: Masaki Yamamoto, Hideaki Nishimori, Takemi Handa, Takashi Fukutomi, Kazuki Kihara, Miwa Tashiro, Takayuki Sato, Kazumasa Orihashi

Published in: Surgery Today | Issue 2/2017

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Abstract

Purpose

The HyperEye Medical System (HEMS) uses indocyanine green (ICG) to visualize blood vessels in coronary artery bypass grafting (CABG). We performed quantitative HEMS assessment to detect grafts at risk of occlusion.

Methods

We assessed the HEMS angiograms of 177 grafts from 69 patients who underwent CABG and compared the results with those of fluoroscopic coronary angiography, by measuring the increasing rate of ICG intensity, average acceleration value, and time to peak luminance intensity.

Results

Grafts in the patent and failed groups showed significant differences in their increasing rate of intensity and average acceleration value. The average accelerations value of ICG intensity of internal thoracic artery (ITA) and saphenous vein (SV) grafts were 112.3 and 144.9 intensity/s2 in the patent group, and 71.0 and 91.8 intensity/s2 in the failed group. The time to peak luminance intensity was 1.7 and 1.4 s in the patent group and 2.3 and 1.9 s in the failed group; these values were not significantly different.

Conclusion

Significant reductions in the ICG intensity rate and average acceleration value can occur in failed grafts. Therefore, quantifiable changes in ICG intensity may help detect minute changes in blood flow.
Literature
1.
go back to reference Tomoaki S, Tohru A. The current status of multi-arterial off-pump coronary artery bypass grafting. Surg Today. 2016;46(1):1–12.CrossRefPubMed Tomoaki S, Tohru A. The current status of multi-arterial off-pump coronary artery bypass grafting. Surg Today. 2016;46(1):1–12.CrossRefPubMed
2.
go back to reference Rubens FD, Ruel M, Fremes SE. A new and simplified method for coronary and graft imaging during CABG. Heart Surg Forum. 2002;5(2):141–4.PubMed Rubens FD, Ruel M, Fremes SE. A new and simplified method for coronary and graft imaging during CABG. Heart Surg Forum. 2002;5(2):141–4.PubMed
3.
go back to reference Detter C, Russ D, Iffland A, Wipper S, Schurr MO, Reichenspurner H, et al. Near-infrared fluorescence coronary angiography: a new noninvasive technology for intraoperative graft patency control. Heart Surg Forum. 2002;5(4):364–9.PubMed Detter C, Russ D, Iffland A, Wipper S, Schurr MO, Reichenspurner H, et al. Near-infrared fluorescence coronary angiography: a new noninvasive technology for intraoperative graft patency control. Heart Surg Forum. 2002;5(4):364–9.PubMed
4.
go back to reference Reuthebuch O, Haussler A, Genoni M, Tavakoli R, Odavic D, Kadner A, et al. Novadaq SPY: intraoperative quality assessment in off-pump coronary artery bypass grafting. Chest. 2004;125(2):418–24.CrossRefPubMed Reuthebuch O, Haussler A, Genoni M, Tavakoli R, Odavic D, Kadner A, et al. Novadaq SPY: intraoperative quality assessment in off-pump coronary artery bypass grafting. Chest. 2004;125(2):418–24.CrossRefPubMed
5.
go back to reference Taggart DP, Choudhary B, Anastasiadis K, Abu-Omar Y, Balacumaraswami L, Pigott DW. Preliminary experience with a novel intraoperative fluorescence imaging technique to evaluate the patency of bypass grafts in total arterial revascularization. Ann Thorac Surg. 2003;75(3):870–3.CrossRefPubMed Taggart DP, Choudhary B, Anastasiadis K, Abu-Omar Y, Balacumaraswami L, Pigott DW. Preliminary experience with a novel intraoperative fluorescence imaging technique to evaluate the patency of bypass grafts in total arterial revascularization. Ann Thorac Surg. 2003;75(3):870–3.CrossRefPubMed
6.
go back to reference Handa T, Katare RG, Sasaguri S, Sato T. Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system: an advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft. Interact CardioVasc Thorac Surg. 2009;9(2):150–4.CrossRefPubMed Handa T, Katare RG, Sasaguri S, Sato T. Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system: an advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft. Interact CardioVasc Thorac Surg. 2009;9(2):150–4.CrossRefPubMed
7.
go back to reference Yamamoto M, Sasaguri S, Sato T. Assessing intraoperative blood flow in cardiovascular surgery. Surg Today. 2011;41(11):1467–74.CrossRefPubMed Yamamoto M, Sasaguri S, Sato T. Assessing intraoperative blood flow in cardiovascular surgery. Surg Today. 2011;41(11):1467–74.CrossRefPubMed
8.
go back to reference Yamamoto M, Orihashi K, Nishimori H, Handa T, Kondo N, Fukutomi T, et al. Efficacy of intraoperative HyperEye Medical System angiography for coronary artery bypass grafting. Surg Today. 2014;45:966–72.CrossRefPubMed Yamamoto M, Orihashi K, Nishimori H, Handa T, Kondo N, Fukutomi T, et al. Efficacy of intraoperative HyperEye Medical System angiography for coronary artery bypass grafting. Surg Today. 2014;45:966–72.CrossRefPubMed
9.
go back to reference Detter C, Wipper S, Russ D, Iffland A, Burdorf L, Thein E, et al. Fluorescent cardiac imaging: a novel intraoperative method for quantitative assessment of myocardial perfusion during graded coronary artery stenosis. Circulation. 2007;116(9):1007–14.CrossRefPubMed Detter C, Wipper S, Russ D, Iffland A, Burdorf L, Thein E, et al. Fluorescent cardiac imaging: a novel intraoperative method for quantitative assessment of myocardial perfusion during graded coronary artery stenosis. Circulation. 2007;116(9):1007–14.CrossRefPubMed
10.
go back to reference Yamamoto M, Orihashi K, Nishimori H, Wariishi S, Fukutomi T, Kondo N, et al. Indocyanine green angiography for intra-operative assessment in vascular surgery. Eur J Vasc Endovasc Surg. 2012;43(4):426–32.CrossRefPubMed Yamamoto M, Orihashi K, Nishimori H, Wariishi S, Fukutomi T, Kondo N, et al. Indocyanine green angiography for intra-operative assessment in vascular surgery. Eur J Vasc Endovasc Surg. 2012;43(4):426–32.CrossRefPubMed
11.
go back to reference Desai ND, Miwa S, Kodama D, Cohen G, Christakis GT, Goldman BS, et al. Improving the quality of coronary bypass surgery with intraoperative angiography: validation of a new technique. J Am Coll Cardiol. 2005;46(8):1521–5.CrossRefPubMed Desai ND, Miwa S, Kodama D, Cohen G, Christakis GT, Goldman BS, et al. Improving the quality of coronary bypass surgery with intraoperative angiography: validation of a new technique. J Am Coll Cardiol. 2005;46(8):1521–5.CrossRefPubMed
12.
go back to reference Balacumaraswami L, Taggart DP. Intraoperative imaging techniques to assess coronary artery bypass graft patency. Ann Thorac Surg. 2007;83(6):2251–7.CrossRefPubMed Balacumaraswami L, Taggart DP. Intraoperative imaging techniques to assess coronary artery bypass graft patency. Ann Thorac Surg. 2007;83(6):2251–7.CrossRefPubMed
13.
go back to reference Okada M, Akita T, Mizuno F, Nakayama A, Morioka K. Beneficial effects of a cardiac support device on left ventricular remodeling after posterior myocardial infarction: an evaluation by echocardiography, pressure-volume curves and ventricular histology. Surg Today. 2016;46(5):621–30.CrossRefPubMed Okada M, Akita T, Mizuno F, Nakayama A, Morioka K. Beneficial effects of a cardiac support device on left ventricular remodeling after posterior myocardial infarction: an evaluation by echocardiography, pressure-volume curves and ventricular histology. Surg Today. 2016;46(5):621–30.CrossRefPubMed
14.
go back to reference Desai ND, Miwa S, Kodama D, Koyama T, Cohen G, Pelletier MP, et al. A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. J Thorac Cardiovasc Surg. 2006;132(3):585–94.CrossRefPubMed Desai ND, Miwa S, Kodama D, Koyama T, Cohen G, Pelletier MP, et al. A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. J Thorac Cardiovasc Surg. 2006;132(3):585–94.CrossRefPubMed
Metadata
Title
Quantitative assessment technique of HyperEye medical system angiography for coronary artery bypass grafting
Authors
Masaki Yamamoto
Hideaki Nishimori
Takemi Handa
Takashi Fukutomi
Kazuki Kihara
Miwa Tashiro
Takayuki Sato
Kazumasa Orihashi
Publication date
01-02-2017
Publisher
Springer Japan
Published in
Surgery Today / Issue 2/2017
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-016-1369-6

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